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NCT Number: NCT07452172

Lumbar and Gluteal Motor Control in Chronic Low Back Pain

The present study aims to evaluate the effectiveness of an 8-week combined lumbar motor control and gluteal muscle strengthening program in individuals with chronic non-specific low back pain

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hospital General Nuestra Señora del Prado

Talavera de la Reina, Toledo, 45600, Spain

Location contact

Ruben fernandez, PhD

CONTACT

[email protected]

+34925803600

About this study

Non-specific low back pain (NSLBP) is defined as axial, non-radiating pain primarily located in the lower back, without signs of a serious underlying condition, spinal stenosis, radiculopathy, or another specific spinal cause. Its lifetime prevalence has been estimated to be as high as 84%, making it one of the most frequent reasons for medical consultation and one of the leading causes of disability worldwide. International clinical practice guidelines recommend therapeutic exercise as a first-line treatment; however, robust conclusions regarding which type of exercise provides the greatest benefit have not yet been established.

Neuromuscular control of the lumbar segment is essential both for the execution of motor tasks and for generating the forces required to stabilize the spine. NSLBP is associated with altered patterns of muscle recruitment, either as a contributing factor to pain onset or as a secondary response to pain. Specifically, altered muscle activation patterns have been observed during both static and dynamic movements, as well as in response to unexpected perturbations.

Individuals with NSLBP frequently exhibit impaired control of the deep trunk mus-cles, such as the transversus abdominis and the deep multifidus, which play a key role in maintaining spinal coordination and stability. Lumbar motor control programs aim to restore coordination, control, and functional capacity of these muscles. This is traditioally achieved by selectively training the deep trunk musculature and progressively integrating it into more complex static, dynamic, and functional tasks.

Moreover, recent studies have demonstrated a close relationship between low back pain and impaired hip motor control, particularly in the presence of reduced mobility and muscle weakness-primarily affecting the hip abductors and extensors-which leads to increased lumbar loading through compensatory mechanisms associated with altered motor patterns secondary to hip stiffness. To date, few randomized controlled trials have evaluated the effect of adding hip muscle strengthening exercises to lumbar motor control programs, and their results have been relatively heterogeneous and inconsistent. Previous studies reported no significant effects on pain or disability, most likely due to the use of unsupervised or time-limited programs, whereas others did observe improvements, although their interventions did not specifically target the transversus abdominis and deep multifidus muscles. Notably, the duration of all previously reported programs was less than 8 weeks, which is considered the minimum period required to achieve greater clinical benefits.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 65 years.
  • Non-specific low back pain with an intensity greater than 3/10 on a visual analogue scale.
  • Symptom duration longer than 3 months.
  • Sufficient understanding of spoken and written Spanish to adequately comprehend the intervention instructions and complete the assessments.

Exclusion criteria

  • Severe lumbar or hip trauma within the previous 6 weeks.
  • Prior vertebral fracture or lumbar disc herniation.
  • Fibromyalgia.
  • Active oncological disease.
  • Diagnosis of a severe psychiatric disorder.
  • Pregnancy.
  • Uncontrolled rheumatologic pathology.
  • Coexisting auto-immune pathology or chronic inflammatory disease.

Treatment and study plan

Lumbar motor control exercises

Device

24 sessions over an 8-week period, at a frequency of three sessions per week (on alternating days -Monday, Wednesday, and Friday-); 60min/session.

Gluteal strengthening exercises

Device

Gluteal strengthening exercises will be performed in the same days as lumbar motor control program.

Primary outcomes

  1. Pain intensity

    Time frame: Baseline; inmediately after intervention.

    It will be measured with a visual analog scale (VAS) of 100 millimeters in length. The subject has to indicate the level of pain he feels, being 0 the absence of pain and 100 the maximum imaginable.

Secondary outcomes

  1. Functionality

    Time frame: Baseline; inmediately after intervention.

    The version adapted to Spanish from the Oswestry Disability Index (ODI) will be used. It comprises 10 items, each scored from 0 to 5 (from no limitation to maximum limitation). The total score (0-100%) is calculated by dividing the sum of the item scores by the maximum possible score and multiplying by 100.

Study contacts

Contact information is provided by the study sponsor or research team.

Ruben Arroyo Fernández, PhD

CONTACT

[email protected]

+34926803600

Rubén Arroyo Fernández, Study director

CONTACT

[email protected]

+34925803600

Sponsors and collaborators

Lead sponsor

University of Castilla-La Mancha

Other

Registry information

Official study title

Efficacy of a Combined Lumbar Motor Control and Gluteal Strengthening Program on Pain and Function in Chronic Non-specific Low Back Pain

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 5, 2026
Registry last updated
Mar 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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