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NCT Number: NCT07240961

Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain. The ESP block is one of the inter-fascicular blocks and it's an easy-to-perform technique.In the literature, it has been reported that Lumbar ESPB provides effective analgesia after a hip surgery.

The purpose of this prospective randomized study was to compare the analgesic effects of the ultrasound-guided lumbar Erector Spinae Plane block on postoperative pain management versus the multimodal analgesia after total hip arthroplasty.

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Key information

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kassab Orthopedic Institute

Manouba, 2010, Tunisia

Location status: Recruiting

Location contact

KAABACHI OLFA OLFA, PROFESSOR

CONTACT

[email protected]

0021098317381

About this study

Patients aged more than 18 years, ASA I-III scheduled for primary total hip arthroplasty with lateral approach and under general anesthesia Patients were randomly assigned, into 1 of 2 groups, namely, group ESPBL and group Placebo, using sealed envelopes

  • For ESPBL group: Lumbar ESP block performed after anesthesia induction. A low-frequency ultrasound probe will be placed longitudinally 2-3 cm lateral to the L4 transverse process. Erector spinae muscle will be visualized on the hyperechoic transverse process. The block needle (100 mm, 22G) will be inserted cranio-caudal direction and following confirmation of the correct position of the needle, between the erectorspinae muscle and the transverse process,30 ml of local anesthetic (0.25% bupivacaine/0.2% ropivacaine) will be administered for the block.
  • For Placebo group: patients had multimodal analgesia without lumbar ESP block Patients will be transferred to continuous care unit for 24 hours.

Post-operative analgesia will include:

  • Paracetamol 1g IV every 8 hours for 1 day then oral paracetamol 1g every 8 hours for 4 weeks.
  • Diclofenac sodium(50mg) 1 tablet x 2 per day for 5 days.
  • PCA morphine (Patient Controlled Analgesia), as a rescue analgesia, programmed as: Bolus of 1mg/ refractory period of 10 min/ maximum dose set up at 10mg every 12h.

The primary outcome of the study is to compare postoperative opioids consumption in the first 24 postoperative hours.

Secondary endpoints:

Secondary outcomes are: intraoperative opioid consumption, postoperative pain scores, sitting position and adverse effects related to opioids.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • primary total hip arthroplasty with lateral approach and under general anesthesia .

Exclusion criteria

  • • Contraindication or refusal to regional anesthesia
  • Contraindication to non-steroidal anti-inflammatory (NSAID's)
  • Allergy to opioids
  • Allergy to paracetamol
  • Creatinine clearance < 30ml/min
  • Weight<50 kg or >100kg
  • Psychiatric disorders and difficulty of communication
  • Lower limb neurological deficit
  • Patients undergoing bilateral or revision total hip replacement

Treatment and study plan

Lumbal Erector Spinae Plane Block

Procedure

Lumbar ESP block performed after anesthesia induction. A low-frequency ultrasound probe will be placed longitudinally 2-3 cm lateral to the L4 transverse process. Erector spinae muscle will be visualized on the hyperechoic transverse process. The block needle (100 mm, 22G) will be inserted cranio-caudal direction and following confirmation of the correct position of the needle, between the erectorspinae muscle and the transverse process,30 ml of local anesthetic (0.25% bupivacaine/0.2% ropivacaine) will be administered for the block.

intravenous pain killers

Procedure

intravenous pain killers

Primary outcomes

  1. morphine consumption

    Time frame: Day 1

    total morphine dose

Secondary outcomes

  1. pain scores

    Time frame: Hour 2, Hour 4, Hour 6, Hour 12, Hour 18, Hour 24 and on Day 2 and Day 7.

    numerical pain rating scale [1 to 10 worse outcome]

  2. intraoperative opioid consumption

    Time frame: end of surgery

    total fentanyl dose

  3. pain on sitting position

    Time frame: Day 1

    numerical pain rating scale [1 to 10 worse outcome]

  4. QR 9 score

    Time frame: Day 2

    quality of recovery score [0 to 18 best outcome]

  5. ROM

    Time frame: Day 1

    Range of mouvement [0° to 90°best outcome]

  6. pain during walk

    Time frame: Day 7

    numerical pain rating scale [1 to 10 worse outcome]

Study contacts

Contact information is provided by the study sponsor or research team.

KAABACHI OLFA

CONTACT

Sponsors and collaborators

Lead sponsor

University Tunis El Manar

Other

Registry information

Official study title

Ultrasound-Guided Lumbal Erector Spinae Plane Block on Postoperative Pain Management After Total Hip Arthroplasty

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 21, 2025
Registry last updated
Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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