Lower Extremity Muscle and Function in the Elderly: Study 2

This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

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Key information

Conditions

Mobility Limitation Behavior Motor Activity Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

70 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jean Mayer USDA Human Nutrition Research Center on Aging

Boston, Massachusetts, 02111, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male and Female 70-85 yrs
Community dwelling
Short Performance Battery Score >9
BMI range 19-32 kg/m2
Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion criteria

Acute or Terminal Illness
MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
Upper or Lower extremity fracture in previous 6 months
Uncontrolled hypertension (150/90mmHg)
Neuromuscular diseases and drugs that affect neuromuscular function
Hormone replacement therapy
Participation in any regular endurance or resistance training exercise during previous 3 months

Treatment and study plan

High velocity low force Power Training

Behavioral

Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Low velocity high force Power Training

Behavioral

Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Primary outcomes

Leg Extensor Muscle Power

Time frame: Change from baseline to Week 16

Leg extensor muscle power measured on pneumatic strength testing equipment at a external force consistent with 70% of the participant maximum leg extensor strength.

Sponsors and collaborators

Lead sponsor

Tufts University

Other

Registry information

Important dates

Study start: 2009
Primary completion: 2011
Study completion: 2011
First posted: Jun 7, 2012
Registry last updated: Dec 10, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed