Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07584746

Lower Extremity Mobility for CAI

This study will be conducted to determine the effect of addition of ankle mobility versus hip mobility exercises to traditional rehabilitation to patients with chronic ankle instability. the main purpose is to answer the following question:

* out of these interventions which would better improve lower limb flexibility, range of motion, severity of functional instability and dynamic postural control?

Researcher will compare between ankle mobility versus hip mobility exercises

Participants will be allocated in 2 experimental groups:

* group A will include 20 patients receiving conventional physiotherapy in addition to ankle mobility exercises * group B will include 20 patients receiving conventional physiotherapy in addition to hip mobility exercises

Patients will receive 3 sessions per week for 6 weeks in a physiotherapy outpatient facility for both groups

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Chronic Ankle Instability, CAI

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (18-30 years old) with chronic ankle instability
  • Patient's Body mass index (BMI) will range from 18.5- 29.9 kg/m2
  • A history of at least one ankle sprain with the initial sprain occurring 12 months prior to study
  • Most recent injury 3 months prior to start of treatment with at least one day of interrupted desired physical activity and associated inflammatory symptoms (pain, swelling, etc.).
  • A history of previous giving way and/or recurrent sprain, and/or feeling of instability to injured ankle.
  • Cumberland Ankle Instability Tool: score of ≤ 24.

Exclusion criteria

  • Other lower extremity injury surgery 6 months before testing
  • Patient suffered an acute sprain in the previous 6 weeks to the start of the study.
  • History of neuromuscular disorders.
  • Systemic diseases that affect balance.

Treatment and study plan

traditional rehabilitation for Chronic Ankle Instability

Other
  • Ankle muscles strengthening exercises
  • balance training

Ankle mobility exercises

Other

9 ankle mobility exercises including: ankle pumps, ankle circles, forward lunges, plantarflexion stretch, calf stretch, squat with overhead reach, heel drops on step, ankle flexion with band and scoops

Hip mobility exercises

Other

8 hip mobility exercises including: 90/90 hip stretch, frog stretch, world's greatest stretch, banded hamstring stretch, backward lunges, butterfly, pigeon stretch and banded hip stretch.

Primary outcomes

  1. lower limb flexibility

    Time frame: 6 weeks

    measure the lower trunk and lower extremity flexibility with modified sit and reach test, sideways split and single legged knee bend test

  2. Range of motion

    Time frame: 6 weeks

    Hip flexion and extension range of motion Ankle dorsiflexion and plantarflexion range of motion

  3. severity of chronic ankle instability

    Time frame: 6 weeks

    using the Arabic version of the Cumberland Ankle Instability Tool, a tool used to describe the severity of chronic ankle instability, with the highest possible score is: 30 and the lowest possible score is: 0 Higher scores indicate better ankle stability, while lower scores indicate higher severity of functional instability

  4. Dynamic postural control

    Time frame: 6 weeks

    using the modified star excursion balance test

Study contacts

Contact information is provided by the study sponsor or research team.

Amal Mounir Mohamed

CONTACT

[email protected]

+201141099494

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Effects of Targeted Mobility Interventions at the Ankle Versus Hip on Clinical and Functional Outcomes in Chronic Ankle Instability

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 13, 2026
Registry last updated
May 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.