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Completed

NCT Number: NCT04181671

Low Resistance Venous Blood Flow Restriction Training (LR-VBFRT) on Biceps Brachii Muscle Performance

Resistance training has been widely recognized as an effective stimulus for increasing skeletal muscle size and strength. This study intends to compare the effects of high resistance training without blood flow restriction and the low resistance training with blood flow restriction training on bicep muscle performance.

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Key information

Conditions

Muscle Weakness Condition

Age range

20 year–28 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

RCRAHS Potohar campus

Rawalpindi, Punjab Province, 44000, Pakistan

About this study

The study is Randomized Control Trail, which is being conducted in RIPHAH COLLEGE OF REHABILITATION SCIENCES. Sample size of 40 individual was calculated using Epitool with 95% confidence interval (CI) and power 80%. Individual will be screened out according to inclusion criteria. Individuals will be allocated randomly into two groups, 20 in high resistance training group and 20 in low resistance training with blood flow restriction group by sealed envelope method.

High resistance training will be use in control group.Low resistance with blood flow restriction training will be used in experimental group.

Assessment will be done on baseline 2-4 days prior to the intervention and after 8 weeks of training.

Data will be analyzed on SPSS version 21.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males
  • Age: 20-28 year
  • Body mass index: 18.5-24.9

Exclusion criteria

  • Vascular Disease
  • Upper Limb Pathology Requiring Surgical Intervention
  • Upper Limb Musculoskeletal Issues
  • Blood Pressure >140/90
  • Coronary Artery Disease
  • Venous Thromboembolism
  • Congenital Cardiac Diseases
  • Syncope, Arrhythmias, Smokers
  • Alcohol Use
  • Supplements Intake
  • whey Protein Intake

Treatment and study plan

Low Resistance training with venous blood flow restriction

Other

Total 20 males will participate in this group after warmup , Blood flow restriction will be provided through sphygmomanometer optimum pressure will be measured through following formula occlusion pressure (mmHg) = 0.514 (SBP) + 0.339 (DBP) + 1.461 (Arm circumference) + 17.236 then 30% of 1RM will be used for training . The standard protocol will be used which is four sets (1st set-30 repetitions, 2nd set-15 repetitions, 3rd set-15 repetitions, and 4th set-15 repetitions) with 30-60 s of interval between sets. ( the cuff must be deflated between sets of exercise) for 8 weeks (24) sessions on non-consecutive days. participants will be re-assessed for all baseline variables after 8 weeks of training biceps curls will be used for training.

Heart Rate and oxygen saturation will be measured during the session through Pulse oximeter

High Resistance training

Other

Total 20 males will participate in this group after warm up. 80% of 1RM will be used for training, 3 sets of 8 repetitions will be used with 30-60 s of interval between sets. for 8 weeks (24) sessions on non-consecutive days.No blood flow restriction will be applied to this group Participants will be re-assessed for all baseline variables after 8 weeks of training. Bicep curls will be used for training.

Primary outcomes

  1. Muscle strength

    Time frame: Baseline

    Handheld dynamometer will be used for measuring muscle strength of bicep muscle of all participants by single examiner

  2. Muscle strength

    Time frame: Post 6 weeks

    Handheld dynamometer will be used for measuring muscle strength of bicep muscle of all participants by single examiner

  3. 1 Repetition maximum

    Time frame: Baseline

    1RM will be assess using Epley's formula of 1RM , RM= w(1+r/30) where "w" is the sub maximal weight and "r" is repetition then percentages of 1RM will be used for training purposes 80% of 1 RM for control group and 30% of 1RM for experimental group.

  4. 1 Repetition maximum

    Time frame: Post 6 weeks

    1RM will be assess using Epley's formula of 1RM , RM= w(1+r/30) where "w" is the sub maximal weight and "r" is repetition then percentages of 1RM will be used for training purposes 80% of 1 RM for control group and 30% of 1RM for experimental group.

  5. Bicep Muscle power

    Time frame: Baseline

    Muscle power will be assesses of all the participants using power formula(Power= W/t= FS/t) for that force (F) will be assessed through dynamometer in newton covered distance (S) will be taken as covered range of motion and will be asses through goniometer (elbow flexion in supinated position). Time (t) will be calculated using stop watch

  6. Bicep Muscle power

    Time frame: Post 6 weeks

    Muscle power will be assesses of all the participants using power formula(Power= W/t= FS/t) for that force (F) will be assessed through dynamometer in newton covered distance (S) will be taken as covered range of motion and will be asses through goniometer (elbow flexion in supinated position). Time (t) will be calculated using stop watch

  7. Bicep muscle endurance testing

    Time frame: Baseline

    Bicep muscle endurance will be calculated prior to the intervention by asking participants to lift light -moderate weight and perform bicep curls in supinated position the total number of repetition they will perform doing complete eccentric and concentric movement of the muscle will be taken as the endurance of the bicep muscle

  8. Bicep muscle endurance testing

    Time frame: Post 6 weeks

    Bicep muscle endurance will be calculated prior to the intervention by asking participants to lift light -moderate weight and perform bicep curls in supinated position the total number of repetition they will perform doing complete eccentric and concentric movement of the muscle will be taken as the endurance of the bicep muscle

  9. Arm circumference

    Time frame: Baseline

    arm circumference will be measured in centimeters at the midpoint between the acromion process and the center of the elbow(by measuring tape)

  10. Arm circumference

    Time frame: Post 6 weeks

    arm circumference will be measured in centimeters at the midpoint between the acromion process and the center of the elbow(by measuring tape)

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of Low Resistance Venous Blood Flow Restriction Training (LR-VBFRT) on Biceps Brachii Muscle Performance

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Nov 29, 2019
Registry last updated
Jan 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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