Skip to main content
OpenTrials
Completed

NCT Number: NCT03049943

Low Level Laser Therapy for Hyposalivation

The aim of this study was to compare the effects of different wave lengths of LLLT on salivation in participants suffering from hyposalivation.

This study included 30 participants whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment and 10th day after treatment was ended.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hyposalivation Mouth Diseases Salivary Gland Diseases Stomatognathic Diseases Xerostomia

Age range

52 year–85 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

School of Dental Medicine, University of Zagreb

Zagreb, 10000, Croatia

About this study

Low level laser treatment has proved to be effective for a wide range of oral pathologies including oral dryness, but the literature still lacks reports of clinical trials and protocols. The aim of this study was to evaluate the effects of two different laser wave lengths on salivation of patients suffering from hyposalivation. This with purpose to possibly find the optimum laser wavelength for the treatment, and to determine the better protocol for the patients suffering from hyposalivation. This study included 30 patients whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured in graduated tubes each day during 10 days, before and after laser treatment and 10th day after treatment was ended.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients suffering from hyposalivation, with medical histories free of radiotherapy and Sjögren's syndrome

Exclusion criteria

  • medical histories of radiotherapy and Sjögren's syndrome

Treatment and study plan

Low level laser

Device

Primary outcomes

  1. Difference in average salivary flow rate, before and after low level laser treatment

    Time frame: 10 days

    The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment

Secondary outcomes

  1. Average salivary flow rate

    Time frame: 1 day (Average salivary flow rate 10th day after the end of LLLT)

    Average salivary flow rate 10th day after the end of LLLT

Sponsors and collaborators

Lead sponsor

University of Zagreb

Other

Registry information

Official study title

Different Low Level Laser Protocols for Therapy of Hyposalivation

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Feb 10, 2017
Registry last updated
Feb 10, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.