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Completed

NCT Number: NCT07536451

Low-Level Diode Laser Therapy on the Acceleration of Osseointegration Around Delayed Dental Implant

Good quality soft tissue determines the possibility not only to obtain full primary wound closure during the bone defect reconstruction, but also assures effective implant treatment and stability of peri-implant condition.Moreover, it is very important to assure the proper emergence profile of the implant supported restorations, which give the opportunity to achieve the highest aesthetic appearance. In the long-term, the correct width and thickness of the attached keratinized tissue is the key point to ensure the stable position of the mucosal line around the implant's neck. The promising outcomes of laser on soft and hard tissue have been demonstrating in a variety of studies. Therefore, the aim of this clinical study is to evaluate the efficacy of LLDLT on enhancing osseointegration and on the peri-implant mucosal tissue around delayed dental implants.

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Key information

Conditions

Dental Implant

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kafr El-sheikh University

Kafr Elsheikh, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients are systemically medically free.
  • Ability to maintain good oral hygiene as evidenced in recall visits.
  • Sufficient mesiodistal and interocclusal space and have an intact buccal bone contours which does not require bone augmentation procedures.
  • Adequate bone quality.
  • Keratinized tissue ≥ 2mm.
  • Thickness of the gingiva ≥ 1 mm.

Exclusion criteria

  • Presence of any systemic disease that could influence the outcome of the therapy.
  • Presence of any risk factor e.g.; smoker, pregnant, lactating patients or any disease affect bone healing.
  • Previous history of periodontal surgical treatment in quadrant selected for the study.
  • Restorations or caries in the area to be treated and non-vital tooth.
  • Adjacent teeth are tilted or rotated.
  • Patients taking medications known to cause affect bone quality.
  • Traumatic occlusion or Para-functional habits such as clenching or bruxism.
  • Participation in other clinical trials.

Treatment and study plan

Dental implant + LLDL

Other

implant placement in the posterior areas and implants will be placed with application of LLDL. Preparation of the alveolus for delayed dental implant placement will be done and LLDL application according to manufacturer instructions

dental implant

Other

It includes ten patients seeking for implant placement at the posterior areas and those patients will be received their implants only without application of LLDL .

Primary outcomes

  1. Change in marginal bone loss

    Time frame: 2 weeks, 1month, 2 months, and 6 months

    To assess the change in marginal bone loss, the linear distance from a fixed reference point-typically the implant shoulder or CEJ-to the highest level of bone-to-tooth/implant contact is measured.

  2. Change in in implant stability

    Time frame: Immediately after surgery, 2 months and 6months postoperative.

    Ostell device will be used to assess implant stability

Secondary outcomes

  1. Change in bone density

    Time frame: 2 weeks, 1month, 2 months, and 6 months

    Radiographic examination of the patients will be done firstly pre-operative then at six months follow-up period post-operative by using CBCT device

Sponsors and collaborators

Lead sponsor

Hams Hamed Abdelrahman

Other

Registry information

Official study title

The Efficacy of Low-Level Diode Laser Therapy on the Acceleration of Osseointegration and Mucosal Phenotype Around Delayed Dental Implant: A Randomized Controlled Clinical Trial

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Apr 17, 2026
Registry last updated
Apr 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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