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NCT Number: NCT07552116

Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia

Objective: The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, were included into ; group (A) received low intensity laser therapy, inspiratory muscle training in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

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Key information

Conditions

Pneumonia Infections Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections

Age range

3 year–5 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

The aim of this study was to detect the impact of low intensity laser therapy on immune system response among DS children with pneumonia. Material and Methods: Forty DS children with bronchopneumonia, mean age of 3.73±1.82 year and were included into 2 equal groups; group (A) received low intensity laser therapy, inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment at a frequency of 3 sessions per week for one month, where the second group (B) received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements of WBCs, IgG, IgA, IgM, RR and SaO2 were obtained for both groups before treatment and after one month at the end of the treatment program.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Dawn Syndrome children with pneumonia
  • Mean age of 3.73±1.82 year
  • Children were in the first attack of bronchopneumonia.

Exclusion criteria

  • Other chest disease

Treatment and study plan

low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

Other

low intensity laser therapy ,muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

Other names: low intensity laser therapy, muscle training using incentive spirometer associated with postural drainage in addition to medical treatment. Measurements

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Other

received inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Other names: inspiratory muscle training using incentive spirometer associated with postural drainage in addition to medical treatment.

Primary outcomes

  1. IgG

    Time frame: at baseline and after one month

    Immunoglobulin-G (mg/dl)

  2. IgA

    Time frame: at baseline and after one month

    Immunoglobulin-A(mg/dl)

  3. IgM

    Time frame: at baseline and after one month

    Immunoglobulin-M (mg/dl)

  4. WBCs

    Time frame: at baseline and after one month

    White blood cells (thousands/mm3)

Secondary outcomes

  1. RR

    Time frame: at baseline and after one month

    Respiratory Rate(breath/minute)

  2. SaO2

    Time frame: at baseline and after one month

    Arterial oxygen saturation(%)

Study contacts

Contact information is provided by the study sponsor or research team.

Mona Mohamed Abdelkhalek, assistance professor

CONTACT

[email protected]

00201024056108

Mona Mohamed Abdelkhalek, assistance professor

CONTACT

[email protected]

00201024056108

Sponsors and collaborators

Lead sponsor

Badr University

Other

Registry information

Official study title

Impact of Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia

Acronym: intervention

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 27, 2026
Registry last updated
Apr 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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