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NCT Number: NCT06443879

Loss and Return of Sensation After Axillary Brachial Plexus Nerve Block - Distally or Proximally

Peripheral regional anesthesia is the current gold standard of opioid-sparing perioperative analgesia, especially in shoulder, upper limb, and leg surgery. Axillary brachial plexus nerve block is one possible block for upper limb surgery. Loss and return of sensation require time and loss of sensation is supposed to spread from the proximal part to the distal part of the upper limb. Interestingly, until now there is no study about the return of sensation related to the anatomic region.

The investigators hypothesize that the loss and return of sensation after axillary brachial plexus nerve block will first occur in the proximal part of the upper limb and last in the distal part.

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Key information

Conditions

Anesthesia

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Balgrist University Hospital

Zurich, Canton of Zurich, 8008, Switzerland

About this study

Peripheral regional anesthesia is the current gold standard of opioid-sparing perioperative analgesia, especially in shoulder, upper limb, and leg surgery.(1-8) Axillary brachial plexus nerve block is one possible block for upper limb surgery.(4, 5, 9) Loss and return of sensation require time. It is known from clinical practice that loss of sensation occurs from the proximal part of the arm to the distal part of the upper limb.

Interestingly, until now there is no study about the return of sensation related to the anatomic region. The investigators hypothesize that return of sensation after axillary brachial plexus nerve block will develop in the same direction like loss of sensation, what means from proximal to the distal part of the upper limb.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Outpatients with planed surgery with axillary brachial plexus nerve block
  • Informed consent as documented by signature
  • Age ≥ 18 years

Exclusion criteria

  • Patients with a known allergy towards the local anaesthetic

Treatment and study plan

Axillary brachial plexus nerve block: loss and return of sensation

Other

Evaluating loss and return of sensation after axillary brachial plexus nerve block

Primary outcomes

  1. Loss of sensation after axillary brachial plexus nerve block

    Time frame: Pre-surgery

    A questionnaire will be used to record the loss of sensation in the upper limb. Sensation loss is recorded separately for the finger, hand, forearm, elbow, and arm. It will distinguish between initial and complete loss of sensation.

  2. Return of sensation after axillary brachial plexus nerve block

    Time frame: Immediately after the surgery

    A questionnaire will be used to record the return of sensation in the upper limb. Sensation return is recorded separately for the finger, hand, forearm, elbow, and arm. It will distinguish between initial and complete return of sensation.

Secondary outcomes

  1. Pain before

    Time frame: Pre-surgery

    Pain score (Numeric Rating Scale: 0 to 10) before loss of sensation after the axillary brachial plexus nerve block on a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable.

  2. Pain after

    Time frame: Immediately after the surgery

    Pain score (Numeric Rating Scale: 0 to 10) after loss of sensation after the axillary brachial plexus nerve block on a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable.

  3. Block failure

    Time frame: Pre-surgery

    Block failure yes or no

  4. Amount of pain medication

    Time frame: Immediately after the surgery up to 2 days

    Amount of pain medication after surgery, measured in mg

  5. Prolongation of hospitalization

    Time frame: Immediately after the surgery

    The patient is expected to be an outpatient. If this does not occur, the days of hospitalization will be recorded.

  6. Patients satisfaction with pain therapy

    Time frame: Immediately after the surgery

    The patient will be asked to rate their satisfaction with the pain therapy on a scale from 0 to 10, with 0 indicating very dissatisfied and 10 indicating very satisfied.

  7. Satisfaction of medical staff with the execution of the axillary brachial plexus nerve block

    Time frame: Immediately after the surgery

    The medical staff will be asked to rate their satisfaction with the execution of the axillary brachial plexus nerve block on a scale from 0 to 10, with 0 indicating very dissatisfied and 10 indicating very satisfied.

Sponsors and collaborators

Lead sponsor

Balgrist University Hospital

Other

Registry information

Acronym: LRNB

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jun 5, 2024
Registry last updated
Nov 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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