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Completed

NCT Number: NCT00140959

Losartan and HCTZ and Amlodipine vs Atenolol and Amlodipine (0954A-309)(COMPLETED)

A study to evaluate the effects of combination losartan versus combination atenolol in patients with ambulatory systolic hypertension.

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Key information

Conditions

Hypertension Cardiovascular Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males or females at least 18 years of age who have ambulatory systolic hypertension.

Treatment and study plan

MK0954, losartan potassium/Duration of Treatment: 18 weeks

Drug

Comparator: losartan, HCTZ, amlodipine, atenolol/Duration of Treatment: 18 weeks

Drug

Primary outcomes

  1. Mean daytime ambulatory systolic blood pressure

Secondary outcomes

  1. Ambulatory BP

  2. Pulse pressure

  3. Trough sitting BP

  4. Percentage of patients who reach goal ambulatory systolic BP

Sponsors and collaborators

Lead sponsor

Organon and Co

Industry

Registry information

Official study title

Antihypertensive Effects of a Fixed-dose Combination of Losartan and Hydrochlorothiazide Plus Amlodipine Versus a Hydrochlorothiazide and Atenolol Combination Plus Amlodipine in Subjects With Ambulatory Systolic Hypertension.

Important dates

Study start
2003
Primary completion
2004
Study completion
2004
First posted
Sep 1, 2005
Registry last updated
Aug 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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