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Completed

NCT Number: NCT05679453

Lornoxicam Versus Etodolac After Third Molar Surgery

Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction

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Key information

Conditions

Pain, Acute Acute Pain Edema Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms Spasm Trismus

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Zülfikar Karabıyık

Kütahya, 43000, Turkey (Türkiye)

About this study

20 patients included in study (4 male, 16 female). Lornoxicam and etodolac was given following lower third molar extraction. Pain was evaluated 2., 6., 12., 24., and 48. hours using VAS. Edema was evaluated by measuring tragus-labial commissure, angulus- lateral canthus of eye and angulus mandible-labial commissure. Trismus was evaluated measuring mouth opening by caliper. Edema and Trismus was evaluated by 48. and 168. hours

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Bilateral mesioangular impacted lower third molar
  • Asymptomatic Third Molar (No history of infection)
  • Systemically Healthy Person
  • Person Between aged 18-30

Exclusion criteria

  • People who are pregnant and lactation process
  • People who had any systemic disease
  • People who are gastrointestinal problems
  • People who are sensitive to drugs used in study
  • Lower Third Molar associated with cysts and infections

Treatment and study plan

Lornoxicam 8 Mg Oral Tablet

Drug

Lornoxicam is a oxicam grup non-steroid antiinflamatuar drug

Other names: Etodolac

Primary outcomes

  1. Pain after wisdom tooth extraction

    Time frame: 2 th hours

    Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)

  2. Edema after wisdom tooth extraction

    Time frame: 48 th hours

    Edema lower third molar removal, Edema was evaluated by using reference line on the face

  3. Trismus after wisdom tooth extraction

    Time frame: 48 th hours,

    Trismus lower third molar removal, trismus was evaluated by using caliper

Secondary outcomes

  1. Pain after wisdom tooth extraction

    Time frame: 6 th hours

    Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)

  2. Pain after wisdom tooth extraction

    Time frame: 12 th hours

    Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)

  3. Pain after wisdom tooth extraction

    Time frame: 24 th hours

    Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)

  4. Pain after wisdom tooth extraction

    Time frame: 48 th hours

    Pain after lower third molar removal, Pain was evaluated with VAS(visual anolog scale)

  5. Edema after wisdom tooth extraction

    Time frame: 168 th hours

    Edema lower third molar removal, Edema was evaluated by using reference line on the face

  6. Trismus after wisdom tooth extraction

    Time frame: 168 th hours

    Trismus lower third molar removal, trismus was evaluated by using caliper

Sponsors and collaborators

Lead sponsor

Kutahya Health Sciences University

Other

Registry information

Official study title

Comparison of Lornoxicam and Etodolac on Edema, Trismus and Pain After Third Molar Surgery

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Jan 11, 2023
Registry last updated
Jan 11, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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