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NCT Number: NCT07197359

Looksmaxxing AI for Chin Deviation Detection

This study aims to evaluate whether an artificial intelligence application called Looksmaxxing AI will be able to correctly identify chin deviation (chin asymmetry) from standard frontal facial photographs. A total of 540 photographs will be included in the study. The eye areas will be covered to protect identity. Each photo will be analyzed by the AI, and its answers will be compared with clinical reality. The accuracy of two versions of the software (Looksmaxxing 4o and 5) will be assessed. The results may help show whether simple photo-based analysis can support early detection of chin asymmetry, especially in areas with limited access to orthodontic examination.

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This study is active but is not currently recruiting participants.

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Key information

Age range

10 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Necmettin Erbakan University

Konya, 42090, Turkey (Türkiye)

About this study

This observational study will investigate the accuracy of the Looksmaxxing AI application in detecting chin deviation based on standardized frontal facial photographs. A total of 540 images will be included. To protect identity, the eye areas of all participants will be covered. The AI will be asked to determine whether chin deviation is present relative to the midline of the face (excluding the nose).

The study population will consist of two equally sized groups:

270 individuals with clinically observed chin deviation (laterognathia)

270 individuals with clinically normal chin position

The responses provided by Looksmaxxing AI will be compared with the clinical reality and recorded for accuracy. Both versions of the software, Looksmaxxing 4o and Looksmaxxing 5, will be analyzed to evaluate their level of consistency with clinical findings. Results will be reported as accuracy percentages. In addition, prediction accuracy will be compared between individuals with and without chin deviation, and the statistical significance of the difference will be tested using the Chi-square method.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Absence of any craniofacial anomaly

No major wound or scar in the facial or neck region

No history of previous orthodontic treatment

For male participants: absence of a long beard that could affect the appearance of the chin

Availability of standardized frontal facial photographs taken in natural head position

Exclusion criteria

  • Photographs in which the patient's face appears slightly angled or turned sideways

Blurred or low-quality photographs with reduced clarity

Treatment and study plan

Looksmaxxing AI Facial Analysis

Other

Participants' standardized frontal facial photographs will be analyzed using the Looksmaxxing AI application (versions 4o and 5) to determine the presence or absence of chin deviation relative to the facial midline.

Primary outcomes

  1. Accuracy of Looksmaxxing AI in Detecting Chin Deviation

    Time frame: At study completion (October 2025)

    The proportion of correct classifications (presence or absence of chin deviation) made by the Looksmaxxing AI application compared to the clinical gold standard, expressed as a percentage.

Sponsors and collaborators

Lead sponsor

Konya Necmettin Erbakan Üniversitesi

Other

Registry information

Official study title

Detecting Asymmetry With Artificial Intelligence: Consistency Evaluation of the Looksmaxxing Application in Photo-Based Facial Analysis

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 29, 2025
Registry last updated
Oct 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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