Skip to main content
OpenTrials
Enrolling by Invitation

NCT Number: NCT06847776

Longitudinal Evaluation of a Fracture Liaison Service

The major objective of this study is to evaluated osteoporosis prevalence, both on computed tomography (CT) and dual x ray absorptiometry (DXA) in patients included in a fracture liaison service (FLS).

The secondary objectives are to evaluate the prevalence of antiosteoporotic treatments indication, of new fractures or mortality; to identify the risk factor for osteoporosis; the study the treatment's observance; to identify the screening threshold to diagnose osteoporosis on CT.

Enrolling by Invitation

Interested in participating?

Request Info

Key information

Conditions

Osteoporosis Bone Diseases Bone Diseases, Metabolic Fractures, Bone Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases Wounds and Injuries

Age range

50 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU Nancy

Vandœuvre-lès-Nancy, 54500, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age >= 50 years
  • Bone fracture due to a fall

Exclusion criteria

  • patient's opposition

Treatment and study plan

Primary outcomes

  1. Osteoporosis prevalence on DXA and CT

    Time frame: during the evaluation in the fracture liaison service FLS and evry year until 5 years

Secondary outcomes

  1. prevalnce of treatment for osteoporosis

    Time frame: during the evaluation in FLS and every year until 5 years

  2. prevalence of new fractures at 1-3 and 5 years

    Time frame: during the evaluation in FLS and at 1, 3 and 5 years

  3. identification of osteoporosis risk factors

    Time frame: at the inclusion in FLS

  4. definition of the CT threshold for bone fragility in this population;

    Time frame: at the inclusion in FLS

  5. study of the correlation dual x ray absorptiometry and computed tomography bone fragility evaluation

    Time frame: at the inclusion in FLS

  6. study of the correlation between FRAX score and DXA

    Time frame: at the inclusion in FLS

  7. study of the correlation between FRAX score and Trabecular bone score TBS

    Time frame: at the inclusion in FLS

  8. study of the correlation between FRAX score and lean mass

    Time frame: at the inclusion in FLS

Sponsors and collaborators

Lead sponsor

Central Hospital, Nancy, France

Other

Registry information

Acronym: FILFRA

Important dates

Study start
2025
Primary completion
2030
Study completion
2030
First posted
Feb 26, 2025
Registry last updated
Feb 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.