Skip to main content
OpenTrials
Completed

NCT Number: NCT06546228

Long Term Predictors of Acute Myocardial Infarction in Patients With Coronary Revascularization

Worldwide, Ischemic heart disease is the single most common fatal disease. One of the most common causes of acute myocardial infarction is represented by obesity. Numerous cardio metabolic variables play a key role in incidence of adverse cardiovascular outcomes. The purpose of this research was to investigate the factors allowing to acute coronary syndrome, related to the metabolic status, to help guide each patient toward early preventing behaviors.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Acute Myocardial Infarction Revascularization

Sex eligibility

All sexes

Study type

Observational

Primary location

Azienda Ospedaliera Universitaria G. Martino

Messina, Italy

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients met the criteria for Acute Coronary Syndrome (ACS) as defined by the Joint European Society of Cardiology/American College of Cardiology Committee.
  • Patients underwent immediate coronary revascularization (primary PCI) for ST-Elevation Myocardial Infarction (STEMI).
  • Patients underwent coronary revascularization (early PCI) within 24 hours for Non-ST-Elevation Myocardial Infarction (NSTEMI).
  • Patients underwent diagnostic coronary angiography following coronary artery bypass graft surgery (CABG).

Exclusion criteria

  • Known coronary artery disease or previous ACS.
  • PCI following CABG.
  • Cardiogenic shock.
  • Atrial fibrillation.
  • Peripheral artery disease.
  • Severe cardiac valve disease.
  • Prosthetic aorta.

Treatment and study plan

No intervention. Only observational.

Other

Only collection of data or parameters already required by the medical examination programmed.

Primary outcomes

  1. Incidence of Acute Myocardial Infarction (AMI)

    Time frame: 7 years

    Occurrence of AMI. Unit of measure: Medical records, electrocardiogram (ECG), cardiac biomarkers

Secondary outcomes

  1. Change in Left Ventricular Ejection Fraction (LVEF)

    Time frame: 7 years

    LVEF before and after revascularization Measurement Tool: Echocardiogram Unit of Measure: Percentage (%) change in LVEF

  2. Incidence of Cardiovascular Death

    Time frame: 7 years

    Occurrence of cardiovascular death Measurement Tool: Medical records Unit of Measure: Number of cardiovascular deaths per patient-year

Sponsors and collaborators

Lead sponsor

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

Other

Registry information

Official study title

Long Term Predictors of Acute Myocardial Infarction in Patients With Coronary Revascularization: a Machine Learning Analysis After a 7 Years Follow-up

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Aug 9, 2024
Registry last updated
Aug 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.