Long Term Outcome Study in Patients With Pituitary Disorders

To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Pituitary Diseases Acromegaly Adenoma Bone Diseases Bone Diseases, Endocrine Brain Diseases Brain Neoplasms Central Nervous System Diseases Central Nervous System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Hyperpituitarism Hypothalamic Diseases Hypothalamic Neoplasms Musculoskeletal Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Nervous System Diseases Nervous System Neoplasms Pituitary Neoplasms Prolactinoma Supratentorial Neoplasms

Sex eligibility

All sexes

Study type

Observational

About this study

A chart audit of around 1500 patients seen in two specific clinics, the Medical Pituitary Clinic and the combined Endocrine/Neurosurgical Pituitary Clinic at the University of Alberta Hospital, will be performed to determine the effectiveness of various treatment strategies on the long term outcome of specific pituitary disorders. The investigator's will collect retrospective demographic (age, sex, ethnicity), clinical (mode of presentation, hormonal parameters) and therapeutic outcome (surgical, medical, expectant and / or radiation treatment; co-morbidities and complications) of patients seen in these two clinics between January 2000 and December 2020.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with confirmed pituitary disease

Exclusion criteria

patients who do not have confirmed pituitary disease

Treatment and study plan

Primary outcomes

Progression free survival after pituitary surgery

Time frame: up to 17 years post surgery

Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence

Sponsors and collaborators

Lead sponsor

University of Alberta

Other

Registry information

Important dates

Study start: 2000
Primary completion: 2026
Study completion: 2026
First posted: Sep 11, 2018
Registry last updated: Mar 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed