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NCT Number: NCT00760331

Long Term Follow up of a Cohort of Children With TCF2 Mutation:Evolution of Endocrine and Renal Function

Anomalies of renal development are well know for patients treated for MODY-5 diabetes due to TCF2 mutation.A recent study confirms the existence of pediatric patients having TCF2 mutation but presenting renal anomalies alone.Endocrine and renal evolution of these patients is unknown.The aim of this study is to follow a cohort of patients with TCF2 mutation and initially presenting renal anomalies alone.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Hepatocyte Nuclear Factor 1-beta Cakut Prostate Cancer, Hereditary, 11

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Limoges

Limoges, France

About this study

Biologic analysis and renal ultrasonography once a year.

After puberty or before kidney transplantation

  • Abdominal and pelvic MRI
  • Intravenous Glucose Tolerance Test

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients presenting an anomaly of renal development due to TCF2 mutation
  • Age<18 years old

Exclusion criteria

  • Anomaly of renal development without TCF2 mutation
  • Age≥18 years old
  • Parents or patients refusing to participate to the study

Sponsors and collaborators

Lead sponsor

University Hospital, Limoges

Other

Registry information

Official study title

A Long Term Follow up of a Cohort of Children With TCF2 Mutation:Evolution of Endocrine and Renal Function

Acronym: TCF2

Important dates

Study start
2008
Primary completion
2033
Study completion
2033
First posted
Sep 26, 2008
Registry last updated
Aug 13, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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