Long Term Dental Effects in Adolescents Who Were Treated for Cancer in Childhood

The investigators aim is to explore associations between specific types of cancer therapy, age at treatment and the presence of dental abnormalities in adolescence.

The study will help identify unique dental changes, malformations and or missing teeth that appear in adolescence as a secondary complication due to anticancer treatment (chemotherapy and or radiotherapy) given in childhood.

Materials and methods:

* Study Group: 200 patients, at least 12 years old, who were treated for Cancer at the age of 0-10 years old. * The following data will be collected: Demographic information, Medical Status, Cancer therapy, Intraoral examination, Oral soft and hard tissue condition and radiographic examination.

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Key information

Conditions

Cancer Neoplasms

Age range

12 year–32 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hadassah Medical Organization

Jerusalem, 91120, Israel

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

were treated for Cancer at the age of 0-10 years old

Exclusion criteria

None

Treatment and study plan

Collecting data

Other

Collecting data from patient records

Primary outcomes

Oral abnormalities associated with cancer therapy.

Time frame: Two years
A medical survey will be filled out with the patient and his legal guardian. A full dental examination will gather all clinical and radiographic findings. The following measures will be noted:
- Description of chemotherapy agents and duration
- Radiotherapy continuation.
- Radiotherapy dosage in Gray units.
- Yes/No questions regarding previous dental trauma.
- Yes/No questions regarding previous dental treatment.
- Questions regarding oral hygiene.
- Questions concerning oral habits.
- Extra oral examination.
- Intra oral clinical findings will be listed by tooth number.
- Radiographic findings will be listed by tooth number.

Sponsors and collaborators

Lead sponsor

Hadassah Medical Organization

Other

Registry information

Official study title

Long Term Oral and Dental Effects in Adolescents Who Were Treated for Cancer in Childhood

Important dates

Study start: 2018
Primary completion: 2021
Study completion: 2021
First posted: Apr 19, 2016
Registry last updated: Jan 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed