Skip to main content
OpenTrials
Completed

NCT Number: NCT00820625

Long-Standing Persistant Atrial Fibrillation-Pulmonary Vein Isolation With or Without Ablation

The chronic success rate, defined as freedom from any atrial tachyarrhythmias will increase from 35% to 60% by ablation of complex fragmented atrial electrograms potentials in addition to pulmonary vein isolation (PVI) as compared to PVI alone in patients with long-standing persistent AF.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiac Conduction System Disease Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Tachycardia

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Asklepios Klinik St. Georg

Hamburg, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • long standing persistent atrial fibrillation > 6 months and < 5 years

Exclusion criteria

  • renal failure
  • left atrial size >55 mm

Treatment and study plan

pulmonary vein isolation

Procedure

common pulmonary vein isolation procedure

pulmonary vein isolation with additional ablation of fragmented potentials

Procedure

common pulmonary vein isolation with additional but also common ablation of fragmented potentials

Primary outcomes

  1. data collection in view of acute and chronic success rate

    Time frame: 12 months

Secondary outcomes

  1. data collection of complications in both groups and also procedure parameters

    Time frame: 12 months

Sponsors and collaborators

Lead sponsor

Asklepios proresearch

Industry

Registry information

Official study title

Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation - Pulmonary Vein Isolation With or Without Ablation of Complex Fragmented Atrial Potentials

Acronym: Alster-Lost

Important dates

Study start
2008
Primary completion
2017
Study completion
2017
First posted
Jan 12, 2009
Registry last updated
Feb 8, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.