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Enrolling by Invitation

NCT Number: NCT07343856

Long COVID Diagnostic Reactivity Assesment Test

This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing.

The method is used to identify individual bioelectrical reactivity associated with the presence and persistence of pathological factors and to assess patient-specific responses to tested medicinal substances.

The study involves a single-session, non-invasive diagnostic procedure without administration of pharmacological treatment. The primary objective is the methodological evaluation of the diagnostic approach and the characterization of the detected bioelectrical response patterns in the studied population.

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Key information

Conditions

Long COVID Autonomic Nervous System Diseases COVID-19 Chronic Disease Coronaviridae Infections Coronavirus Infections Disease Attributes Infections Lung Diseases Nervous System Diseases Nidovirales Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Viral Post-Acute COVID-19 Syndrome Post-Acute Sequelae of SARS-CoV-2 Infection Post-Infectious Disorders Primary Dysautonomias RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Research Institute of Virology

Tashkent, 100194, Uzbekistan

About this study

This study is a diagnostic clinical investigation designed to evaluate bioelectrical response patterns assessed by electro-acupuncture-based medicament testing.

The method is used to identify individual bioelectrical reactivity associated with the presence and persistence of pathological factors and to assess patient-specific responses to tested medicinal substances.

The study involves a single-session, non-invasive diagnostic procedure without pharmacological treatment. The primary objective is the methodological evaluation of the diagnostic approach and the characterization of the detected bioelectrical response patterns in the studied population.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years or older
  • History of confirmed SARS-CoV-2 infection
  • Persistent symptoms consistent with Long COVID lasting ≥12 weeks after acute infection
  • Ability to provide informed consent
  • Willingness to undergo non-invasive bioelectrical diagnostic assessment

Exclusion criteria

  • Acute infectious disease at the time of enrollment
  • Severe uncontrolled medical or psychiatric conditions that may interfere with diagnostic assessment
  • Implanted electronic medical devices (e.g., pacemaker)
  • Pregnancy or breastfeeding
  • Inability to comply with study procedures

Treatment and study plan

Electrodiagnostic Bioelectrical Assessment

Diagnostic Test

A non-invasive diagnostic procedure performed during a single session to assess bioelectrical response patterns associated with viral antigen persistence. Measurements are obtained using standardized bioelectrical assessment techniques without administration of any therapeutic agents or interventions.

Primary outcomes

  1. Number of Participants With Bioelectrical Response Patterns Consistent With Viral Persistence

    Time frame: At enrollment (single diagnostic session)

    Non-invasive diagnostic assessment using electroacupuncture-based medicament testing to identify bioelectrical response patterns consistent with viral antigen persistence in participants with post-viral conditions.

Secondary outcomes

  1. Distribution of Bioelectrical Reactivity Patterns During Medicament Testing

    Time frame: Baseline(Day 1)

Sponsors and collaborators

Lead sponsor

Oncology Center,Ministry Of Heath,Uzbekistan

Other

Registry information

Official study title

Development of a Personalized Alternative Non-invasive Rapid Diagnostic Test for SARS-CoV-2 in Patients With Long COVID

Acronym: EAV-LONGCOVID

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Jan 15, 2026
Registry last updated
Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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