Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT04404777

Local Recurrence Due to Rectal Cancer in Sweden

The aim of this retrospective national registry study is to validate the reporting of local recurrence in the registry. Another aim is to identify preoperative risk factors for local recurrence. This can in turn indicate the need for a more intense follow-up. The treatment of local recurrence, including the impact of the multidisciplinary team conference (MDT) and the surgical procedure and the referral pathways of local recurrences will also be determined.

We aim to evaluate treatment outcome after local recurrence for patients operated or treated between 2007-2018.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Conditions

Rectal Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Dept. of Surgery, Sahlgrenska University Hospital/Ostra

Gothenburg, SE 416 85, Sweden

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Rectal cancer with a curative intent

Exclusion criteria

  • Rectal cancer without curative intent

Treatment and study plan

Treatment for local recurrence with surgery or other treatments

Procedure

All types of treatment for local recurrence will be evaluated

Primary outcomes

  1. Number of local recurrences

    Time frame: Between 2007-2018

  2. 3 year survival

    Time frame: 3 years

Secondary outcomes

  1. Percentage R0 resection after local recurrence

    Time frame: 1-2 months after initiated treatment

  2. MDT effect on treatment of local recurrence

    Time frame: 1-3 months after diagnosis of recurrence

  3. Reported metastases

    Time frame: 5 years

    Number of patients with metastasis reported vs actual

  4. MRI features at primary diagnosis and relation to recurrence

    Time frame: 2 months

    MRI evaluation by radiologist related to recurrence

Sponsors and collaborators

Lead sponsor

Sahlgrenska University Hospital

Other

Registry information

Official study title

Local Recurrence Due to Rectal Cancer in Sweden - the Actual Incidence, Treatment and Outcome After Treatment

Acronym: LERIS

Important dates

Study start
2022
Primary completion
2023
Study completion
2027
First posted
May 28, 2020
Registry last updated
Jun 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.