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Completed

NCT Number: NCT05205226

Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment

This study aimed to confirmed that local radiotherapy for residual lesions can significantly prolong the efficacy of chemotherapy combined with immunotherapy in the initial treatment of advanced non-small cell lung cancer.

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Key information

Conditions

Non Small Cell Lung Cancer Bronchial Neoplasms Carcinoma, Bronchogenic Carcinoma, Non-Small-Cell Lung Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hunan Cancer Hospital

Changsha, Hunan, 410013, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ≥18，Advanced Non-small Cell Lung Cancer Confirmed by Histopathology Patients received platinum-based chemotherapy combined with immunotherapy

Exclusion criteria

  • EGFR/ALK/ROS1 driver gene mutation
  • Chemotherapy only
  • Concurrent radio-chemotherapy
  • Surgery
  • Single-agent immunotherapy
  • No treatment information available

Treatment and study plan

Primary outcomes

  1. PFS

    Time frame: January 2018 to June 2021

    Progression free survival time

Secondary outcomes

  1. RT

    Time frame: January 2018 to June 2021

    radiotherapy control time

Sponsors and collaborators

Lead sponsor

Hunan Province Tumor Hospital

Other

Registry information

Official study title

Efficacy and Safety of Local Radiotherapy for Residual Tumor Lesions During the First-line Treatment of Advanced Non-small Cell Lung Cancer: a Retrospective-real World Study

Important dates

Study start
2018
Primary completion
2021
Study completion
2022
First posted
Jan 25, 2022
Registry last updated
Jan 25, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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