Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4

Primary outcomes

1. Hemorrhage Resorption Rate

   Time frame: Hemorrhage resorption rate tracking starts from date of identified intraventricular hemorrhage on head ultrasound (usually within 1 week of life) and head ultrasounds weekly up to 4 months old

   Measure rate at which neonate intraventricular hemorrhage is resorbed via serial head ultrasounds

2. Anterior Horn Width

   Time frame: Ventricle volume tracking starts from date of identified intraventricular hemorrhage on head ultrasound (within 1 week of life) performed through weekly head ultrasounds up to 4 months old

   Measure rate at which neonate intracranial pressure changes using anterior horn width (mm) derived from serial head ultrasounds.

3. Neurosurgical Interventions

   Time frame: Number of neurosurgical interventions starts at birth and continues up to 4 months old

   number of patients requiring neurosurgical intervention

4. Neurodevelopmental Outcomes at 6 months and 12 months of age

   Time frame: Two time points at 6 months of age and 12 months of age

   A phone survey will be conducted inquiring which developmental milestones have been met at 6 months (i.e., sitting independently, reaching to grab toys, knows familiar people, takes turns making sounds with care giver) and 12 months (plays interactive games, says mama/dada, looks for hidden objects, cruises, pincer grasp)

5. Ventricular Index

   Time frame: Ventricle volume tracking starts from date of identified intraventricular hemorrhage on head ultrasound (within 1 week of life); and subsequent weekly head ultrasounds performed up to 4 months old

   Measure rate at which neonate intracranial pressure changes using ventricular index (mm) derived from serial head ultrasounds.

6. Head Circumference

   Time frame: Head Circumference tracking starts from birth and is performed daily up to 4 months old

   Measure rate at which neonate intracranial pressure changes via head circumference (cm).