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NCT Number: NCT06866522

Light Reflection on Human Skin in Whole-Body Photobiomodulation Therapy

Photobiomodulation therapy (PBMT) is based on exposing biological tissues to low-intensity light, with effects depending on the light-tissue interaction. When irradiated without skin contact, part of the incident light is reflected and lost. In this context, the amount of reflected light in PBMT applied without skin contact, as well as the influence of skin phototype, has not yet been established. Objective: To quantify the reflection of light from PBMT on the skin of men and women aged 18 to 30 years, considering skin phototypes. Methodology: Participants will be divided into three groups based on skin phototype (Group 1: phototypes I and II; Group 2: phototypes III and IV; Group 3: phototypes V and VI) and sex. They will be subjected to whole-body PBMT with red light (660 nm; 31.85±3.85 mW; 45.50±5.07 mW/cm²) and infrared light (850 nm; 25.29±2.99 mW; 36.13±4.27 mW/cm²) at 20 cm from the light-emitting source, with measurement of light reflection in the regions of the brachial biceps, abdomen, lumbar, anterior and posterior thigh, and calf using a power and energy analyzer (powermeter PM100D and sensor S130C, 0.7 cm²). Data will be analyzed for normality and groups were compared with a significance level of 5%

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Key information

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Federal University of São Carlos (UFSCar)

São Carlos, São Paulo, 13565-905, Brazil

Location status: Recruiting

Location contact

Lara M Bataglia Esposito, PT

CONTACT

[email protected]

+55 16 3351-8985

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male and female
  • age between 18 and 30 years
  • body mass index (BMI) between 18.5 and 29.9 kg/m2.

Exclusion criteria

  • tattoo in the light reflection assessment areas
  • history of skin cancer
  • skin lesions such as open wounds in the mid-thigh, abdomen, biceps brachii, back and calf
  • patients with cognitive difficulty reporting thermal sensation

Treatment and study plan

Whole-Body Photobiomodulation Therapy

Device

Whole-body Photobiomodulation Therapy applied for approximately 10 minutes, being 5 minutes with the red wavelength and 5 minutes with the infrared wavelength.

Primary outcomes

  1. Light Reflection

    Time frame: Acute measurement. The measurement will be performed just during the light therapy irradiation, on the day of the procedure.

    Light reflection will be measured in mW with a PowerMeter Device in the angles of 30º, 60º and 90º considering the participant in front of the whole-body photobiomodulation therapy device.

Sponsors and collaborators

Lead sponsor

Universidade Federal de Sao Carlos

Other

Registry information

Official study title

Light Reflection on Human Skin in Whole-Body Photobiomodulation Therapy: Clinical Trial

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Mar 10, 2025
Registry last updated
Mar 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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