Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans

PRIMARY OBJECTIVE:

I. To expand an existing couple-based behavioral intervention developed for African American (AA) or Hispanic men on active surveillance (Watchful Living; protocol #: 2017-0556) to AA prostate cancer (PCa) survivors who underwent active treatments to examine its feasibility of recruiting AA PCa survivor-partner dyads (N = 40 dyads) and implementing a lifestyle intervention.

SECONDARY OBJECTIVES:

I. Evaluate a preliminary efficacy of the intervention in improving quality of life, physical activity, nutrient intake, and inflammation.

II. Explore psychosocial mediators and moderators of the intervention. III. Conduct a process evaluation. IV. Assess healthcare-provider level factors (with N=15 providers) that influence both survivors' and partners' healthy lifestyle behaviors.

OUTLINE: Patients and their partners are randomized to 1 of 2 groups.

GROUP I: Patients and their partners receive an exercise plan and printed materials that includes instructions for walking or other moderate-intensity activities. Patients and their partners also receive coaching calls discussing physical activity and diet related questions, each lasting 45-60 minutes and occurring every 2 weeks for 6 months. In addition, patients and their partners complete 2 nutrition counseling sessions over 1 hour each at baseline and before month 3 with an MD Anderson registered dietitian.

GROUP II: Patients and their partners receive information/materials regarding physical activity and healthy eating.

PROVIDER INTERVIEWS: Healthcare providers participate in an interview regarding their opinions on family-focused care and its ability to improve health behaviors.

Inclusion criteria

• To be eligible, prostate cancer survivors must self-identify as black or African American
• Prostate cancer survivors must have 0-III stage prostate cancer
• Prostate cancer survivors must have completed therapy (e.g., surgery, chemotherapy [chemo] and/or radiation)
• Prostate cancer survivors must enroll with a spouse or a romantic partner
• Prostate cancer survivors must not meet physical activity recommendation (i.e., 150 minutes of moderate intensity physical activity per week)
• Prostate cancer survivors must be willing and able to be physically active, as determined by responses to the Physical Activity Readiness Questionnaire (PAR-Q)
• Prostate cancer survivors must not participate in another physical activity, diet, or lifestyle program
• Prostate cancer survivors must have a valid home address and telephone number
• Prostate cancer survivors must be able to access internet over a smartphone or a computer at home or other location (e.g., work, church, library, community center, etc.)
• To be eligible, spouses or romantic partners must be >=18 years of age
• Spouses or romantic partners must enroll with a spouse or a romantic partner with prostate cancer
• Spouses or romantic partners must live together with the survivors
• Spouses or romantic partners must not have major health problems (e.g., cancer, dementia, stroke, and heart and lung diseases)
• Spouses or romantic partners must be willing and able to be physically active, as determined by responses to the Physical Activity Readiness Questionnaire (PAR-Q)
• To be eligible, healthcare providers must be currently providing care with individuals diagnosed with prostate cancer
• Any professionals such as surgical and medical oncologists, fellows, nurse practitioners, physical assistants, and primary care physicians will be eligible

Exclusion criteria

• Prostate cancer survivors will be excluded if they are not married or partnered
• Prostate cancer survivors will be excluded if they have an active noncutaneous malignancy at any site
• Prostate cancer survivors will be excluded if they had a prior history of other cancer or have metastatic cancer
• Prostate cancer survivors will be excluded if they have planned concomitant immunotherapy, hormonal therapy, chemotherapy, or radiation therapy during the study period
• Prostate cancer survivors will be excluded if they are on active surveillance
• Prostate cancer survivors will be excluded if they enrolled in a protocol #: 2017-0556
• Prostate cancer survivors will be excluded if they are not able to understand and speak English
• Spouses or romantic partners who are not able to understand and speak English will be excluded
• Also, spouses or romantic partners who enrolled in a protocol (#2017-0556) will be excluded
• There are no exclusion criteria for healthcare providers