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Completed

NCT Number: NCT03671408

Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients

Objectives: The outcomes of heart transplantation are very favorable but inflammation still plays a critical role in deterioration of chronic transplants. Periodontal diseases are not only limited to supporting structures of the teeth, they also cause systemic inflammation. Based on the importance of inflammation in heart transplant recipients and the association between periodontal disease and systemic inflammation, this study explored whether periodontitis may be a modifier of serum high-sensitivity C-reactive protein (HsCRP) in heart transplant patients.

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Key information

Conditions

Heart Transplant Failure CRP Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

11 year–65 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

be clinically stable be at least 1 year post-transplant; no history of antibiotic use during the preceding 4 months have had no periodontal treatment within the previous year.

Exclusion criteria

having other systemic infections

Treatment and study plan

clinical measurements

Other

only clinical parameters were recorded

Other names: no intervention was made

Primary outcomes

  1. hscrp levels

    Time frame: day 1

    serum hscrp levels were compared between the groups

Sponsors and collaborators

Lead sponsor

Baskent University

Other

Registry information

Official study title

Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients With and Without Periodontitis

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Sep 14, 2018
Registry last updated
Sep 14, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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