Faculty of oral and dental medicine
Cairo, Egypt
NCT Number: NCT05448937
The aim of this study is to evaluate the clinical and radiographic success of Lesion Sterilization And Tissue Repair [ LSTR] antibiotic paste versus Zinc Oxide and Eugenol pulpectomy in the treatment of non-vital primary molars.
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Notify Me5 year–7 year
All sexes
Interventional
Phase 2 / Phase 3
Cairo, Egypt
Primary teeth with infected root canals are a common problem, particularly in patients where the infection has reached the peri radicular tissues .
Among the pastes used in the pulp therapy of primary teeth with pulp necrosis, zinc oxide and eugenol paste has been a reference in dentistry since 1930. Endodontic treatment using zinc oxide and eugenol paste has shown satisfactory clinical and radiographic results, requires mechanical chemical preparation before filling root canals.
The main difficulties of endodontic treatment of primary molars are related to the anatomical complexity of the root canals and the long time needed to carry out the treatment. The additional difficulty involved in diagnosing root resorption is a limiting condition for determining the actual working length and instrumentation.
Other pastes have been studied, such as those containing antibiotics in their composition, thus dispensing with root canal instrumentation (such as lesion sterilization and tissue repair using triple antibiotic paste in treatment of non-vital primary molars.
Lesion sterilization and tissue repair using triple antibiotic paste has relevant clinical and radiographic success rates in treatment of non-vital primary molars.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Pulp therapy for necrotic primary molars
Pulp therapy for necrotic primary molars
Time frame: 1 month
Measured by verbal question to patient/parents
Time frame: 3 months
Measured by verbal question to patient/parents
Time frame: 6 months
Measured by verbal question to patient/parents
Time frame: 1 month
Percussion test using back of a dental mirror
Time frame: 3 months
Percussion test using back of a dental mirror
Time frame: 6 months
Percussion test using back of a dental mirror
Time frame: 1 month
Visual examination
Time frame: 3 months
Visual examination
Time frame: 6 months
Visual examination
Time frame: 1 month
Mobility test
Time frame: 3 months
Mobility test
Time frame: 6 months
Mobility test
Time frame: 6 months
Radiographic examination
Time frame: 6 months
Radiographic examination
Cairo University
Other
Clinical And Radiographic Evaluation Of Lesion Sterilization And Tissue Repair Versus Zinc Oxide And Eugenol For Treatment of Necrotic Primary Molars
Acronym: LSTR
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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