Left Ventricular Pacing Vectors Effectiveness to Narrow Phrenic Nerve Stimulation

The primary endpoint of the study aims at demonstrating that the three left ventricular polarities in the Cardiac Resynchronisation Therapy-Defibrillator could bypass phrenic nerve stimulation at least in 90% of implants.

Success was defined as an absence of phrenic nerve stimulation (threshold > 7V) or in case of phrenic nerve stimulation occurrence (threshold < 7V), as the resolution of the phrenic nerve stimulation by reprogramming one of the 3 left ventricular pacing polarities available in the device : left ventricular tip- left ventricular ring (bipolar), left ventricular tip- right ventricular ring (pseudo-bipolar) and left ventricular ring-right ventricular coil.

Any occurrence of phrenic nerve stimulation without resolution by reprogramming was considered as a failure.

Inclusion criteria

• Eligible for an implantation of a Cardiac Resynchronization Therapy-Defibrillator according to relevant regulations (will be only tolerated primo-implantation and upgrade)
• Patient scheduled for implantation of a Cardiac Resynchronization Therapy-Defibrillator
• Patient has given his informed consent

Exclusion criteria

• Any contraindication for Implantable Cardioverter Defibrillator therapy
• Heart transplantation or waiting for heart transplantation
• Implanted with a ventricular assist device (VAD)
• Inability to understand the purpose of the study or to cooperate
• Not available for routine follow-up visits
• Life expectancy less than 12 months
• Age of less than 18 years and et pregnancy
• Under guardianship