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NCT Number: NCT00901602

Lebanese Interhospital Pneumococcal Surveillance Program

Streptococcus pneumoniae (pneumococcus) is a bacterium that causes severe infections in children and adults such as meningitis, pneumonia, and blood stream infection. There are many types of these bacteria defined by the type of sugar coat that they have. These are classified as serotypes. There are common serotypes that cause severe disease and are preventable by vaccination of children. Other less common types are more difficult to prevent. The investigators aim to determine the serotypes that cause invasive pneumococcal disease in Lebanon and to study their sensitivity to different antibiotics. The investigators will collect bacterial isolates from different hospitals in Lebanon isolated from the blood or spinal fluid of patients with invasive pneumococcal disease. This information will help the investigators determine the usefulness of available pneumococcal vaccines in preventing these infections. The data will be distributed to all primary care physicians treating children in Lebanon and will be shared with the Ministry of Health.

Recruiting

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Key information

Age range

1 day and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Samples included in the study are those that are:
  • culture proven
  • invasive pneumococcal infections
  • in patients of all ages admitted to different hospitals all over Lebanon
  • Acceptable samples include:
  • positive isolates from blood
  • cerebrospinal fluid
  • other normally sterile body sites such as empyema fluid, abscesses, joint fluid, middle ear fluid obtained by tympanocentesis in the operating room, and lung needle aspiration

Exclusion criteria

  • non S. pneumoniae isolates

Treatment and study plan

Primary outcomes

  1. Serotype prevalence of S. pneumoniae in invasive pneumococcal disease

    Time frame: yearly

Secondary outcomes

  1. Determine the antibiotic sensitivity of S. pneumoniae and the association with specific serotypes

    Time frame: yearly

Study contacts

Contact information is provided by the study sponsor or research team.

Ghassan S Dbaibo, M.D.

CONTACT

[email protected]

+961-1-749235 ext. 5440

Mireille Lteif, RN

CONTACT

[email protected]

+961-1-350000 ext. 5752

Sponsors and collaborators

Lead sponsor

American University of Beirut Medical Center

Other

Collaborators

  • Pfizer
  • PneumoADIP

Registry information

Official study title

Lebanese Interhospital Pneumococcal Surveillance Program (LIPSP)

Acronym: LIPSP

Important dates

Study start
2005
Primary completion
2030
Study completion
2030
First posted
May 14, 2009
Registry last updated
Feb 3, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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