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NCT Number: NCT07369843

LASER Effects Blood Flow

This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.

Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL.

In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel)

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Key information

Conditions

Pain Management Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

20 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.

Study will recruit healthy volunteers (age 20-60; having no diabetes, hypertension, or other medical problem) and non-invasively monitor their electrocardiogram and digital pulse in response to LPL (with an intensity for relieving pain).

In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel) at the site 2 cm distal to the applying site.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age from 20-45

Exclusion criteria

  • no medical history of diabetes, hypertension, or other medical problem

Treatment and study plan

physical therapy (low power LASER)

Other

Low power laser with an intensity for pain relieving will be applied to volunteers

Primary outcomes

  1. heart rate

    Time frame: Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.

    the heart rate before, during, and after low power LASER

Study contacts

Contact information is provided by the study sponsor or research team.

Chun-Ming Hsieh, MS

CONTACT

[email protected]

+886-(03)361-3141 ext. 8714

Tzer-Bin Lin, Ph.D.

CONTACT

+886-0935-972505

Sponsors and collaborators

Lead sponsor

Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres

Other

Registry information

Official study title

Effects of Low Power LASER on the Heart Rate Variability of Human Subjects

Acronym: LASERBF

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 27, 2026
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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