Skip to main content
OpenTrials
Completed

NCT Number: NCT04279080

LARS in Ovarian Cancer Patients

Background:

Low anterior resection syndrome (LARS) is a common functional disorder after low anterior resection impacting quality of life. Data on LARS derives nearly exclusively from rectal cancer studies. Therefore, the study was designed to assess LARS in advanced epithelial ovarian cancer (EOC) patients, who underwent rectal resection and to compare it with a female rectal cancer cohort.

Methods:

A cross-sectional multi-centre analysis was performed for female patients suffering from either rectal or EOC who received a low anterior resection as part of their therapy regimen. None of the patients received pre- or postoperative radiotherapy. LARS was defined by using the validated LARS score and its severity was divided into "no", "minor" and "major LARS".

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Low Anterior Resection Syndrome Colonic Diseases Digestive System Diseases Gastrointestinal Diseases Intestinal Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Rectal Diseases

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • low anterior resection because of ovarian or rectal cancer

Exclusion criteria

  • neoadjuvant or adjuvant radiotherapy

Treatment and study plan

low anterior resection syndrome evaluation

Other

evaluation of postoperative functional bowel outcome

Primary outcomes

  1. functional bowel outcome after low anterior resection

    Time frame: 1 year

    low anterior resection syndrome score, questionnaire via telephone call or personal contact

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Registry information

Official study title

Low Anterior Resection Syndrome (LARS) in Ovarian Cancer Patients - a Multi-centre Comparative Analysis.

Important dates

Study start
2003
Primary completion
2018
Study completion
2018
First posted
Feb 20, 2020
Registry last updated
Feb 20, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.