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OpenTrials
Completed

NCT Number: NCT05373602

LARS for Chinese Patients

Low anterior resection syndrome (LARS) frequently occurs in patients undergoing low anterior resection (LAR). However, the incidence, exact mechanism and risk factors of major LARS largely variate in different studies. Considering varieties and differences of patient characteristics between Chinese patients and the western ones, this retrospective study aims to investigate the incidence of LARS in Chinese patients undergoing laparoscopic LAR, and to explore perioperative risk factors that might be associated with major LARS. Consequent patients undergoing laparoscopic LAR and free from disease recurrence from January 2015 to May 2021 were issued with LARS questionnaire. Incidence of LARS and patient data were collected and analyzed.

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Key information

Conditions

Incidence and Risk Factors of Low Anterior Resection Syndrome

Sex eligibility

All sexes

Study type

Observational

Primary location

the Third Affiliated Hospital of Sun Yat-Sen University

Guangzhou, Guangdong, 510630, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnosed as rectal cancer and underwent radical laparoscopic LAR and straight colorectal/coloanal anastomosis (with or without a protective stoma) by a same surgical team

Exclusion criteria

either local or distal recurrence, severe complications such as postoperative anastomotic leakage, failure of protective stoma closure, data missed and no responding to LARS questionnaire

Treatment and study plan

LARS questionnaire

Diagnostic Test

Eligible participants were issued with LARS questionnaire (Chinese version) by E-mail, message, phone or face to face interview.

Primary outcomes

  1. incidence of LARS

    Time frame: at least 1 months postoperatively

    incidence of Low Anterior Resection Syndrome

  2. incidence of major LARS

    Time frame: at least 1 months postoperatively

    incidence of major Low Anterior Resection Syndrome

Sponsors and collaborators

Lead sponsor

Third Affiliated Hospital, Sun Yat-Sen University

Other

Registry information

Official study title

The Incidence and Risk Factors of Low Anterior Resection Syndrome: Basing on Data of Chinese Patients From a Single Center

Important dates

Study start
2015
Primary completion
2021
Study completion
2021
First posted
May 13, 2022
Registry last updated
May 13, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.