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Completed

NCT Number: NCT01628250

Laparoscopic Complete Mesocolic Excision on Colon Cancer

Laparoscopic complete mesocolic excision is a concept that using laparoscopic surgery technique to perform a resection for colon cancer. Besides, the segment of the colon containing the tumor, the resection area should include an intact mesocolon as an envelope to encase the possible route for metastasis. The routes include blood vessels, lymphatic drain and etc. Such hypothesis predicts better histopathological and higher oncological results which turns into better survival rate and better quality of life.

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Key information

Conditions

Operation Finding Complications Neoplasms Recurrence Pathology Quality of Life

Age range

18 year–79 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ruijin Hospital affiliated to Shanghai Jiaotong University school of medicine

Shanghai, Shanghai Municipality, 200025, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with pathologically confirmed colon cancer
  • Signed consent

Exclusion criteria

  • History of malignancy
  • Intestinal obstruction or perforation
  • Evidence of metastasis by preoperative examinations
  • Deformity of spine
  • Emergency case
  • BMI > 29

Treatment and study plan

laparoscopic complete mesocolic excision

Procedure

laparoscopic complete mesocolic excision would be applied on randomized group of patients suffering colon cancer and possessing no marked surgical anti-indications. Lap.CME facilitaes medial approach to complete the procedure. CME and HMA are the two arms of the medial approach utilized.

Other names: laparoscopic CME, Complete Medial Approach (CMA), Hybrid Medial Approach (HMA)

D3-laparoscopic colectomy

Procedure

D3-laparoscopic colectomy would be applied on randomized group of patients suffering colon cancer and possessing no marked surgical anti-indications.

Other names: D3 laparoscopic colectomy

Primary outcomes

  1. Histopathological Outcomes Obtained Through the Surgeries

    Time frame: 14 days after the surgery

    number of lymph nodes retrieved

Secondary outcomes

  1. Survival Rate

    Time frame: 3 years after the surgery

    The follow up to the patients after the surgery to evaluate the oncological results of the technique

Sponsors and collaborators

Lead sponsor

Bo Feng

Other

Registry information

Official study title

Clinical Research on the Efficacy and Feasibility of Laparoscopic Complete Mesocolic Excision on Colon Cancer: A Randomized Controlled Study

Acronym: LCME

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Jun 26, 2012
Registry last updated
Nov 15, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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