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OpenTrials
Completed

NCT Number: NCT03267849

Lamina Cribrosa Depth Change With Change in Eye Pressure

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

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Key information

Conditions

Glaucoma, Open-Angle Eye Diseases Glaucoma Ocular Hypertension

Age range

21 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Johns Hopkins University

Baltimore, Maryland, 21287, United States

About this study

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • persons who consent to drink water and be imaged

Exclusion criteria

  • non-consenting persons
  • those who cannot be imaged

Treatment and study plan

wearing swimming goggles or having laser suturelysis

Other

Two images will be compared in each subject at two different eye pressures with the higher pressure having been produced by the interventions

Primary outcomes

  1. Change in anterior lamina cribrosa depth

    Time frame: Up to 2 months

    OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

  • Topcon Corporation

Registry information

Important dates

Study start
2017
Primary completion
2024
Study completion
2024
First posted
Aug 30, 2017
Registry last updated
Oct 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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