Lactoferrin Efficacy Versus Ferrous Sulfate in Treatment of Patients With Iron Deficiency Anemia

Lactoferrin (Lf) is a mammalian cationic iron binding glycoprotein belonging to the transferrin family which was discovered 70 years ago, and isolated simultaneously from human and bovine milks in 1960. It is widely distributed in all biological fluids and is also expressed by immune cells, which release it under stimulation by pathogens

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Key information

Conditions

Iron Deficiency Anemia Treatment Anemia Anemia, Hypochromic Anemia, Iron-Deficiency Hematologic Diseases Hemic and Lymphatic Diseases Iron Deficiencies Iron Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

2 year–15 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

AssuitU

Asyut, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all patients with iron deficiency anemia from 2 to 15 years old

Exclusion criteria

Anemia rather than iron deficiency anemia.
Family history of blood disease.
Patients with thalassemia trait.
Patients with chronic illness.

Treatment and study plan

Lactoferrin Bovine

Drug

treatment for 30 days

Other names: Pravotin sachet

Ferrous Sulfate

Drug

treatment for 30 days

Other names: ferrovit syrup

Primary outcomes

comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.

Time frame: 30 days

Complete blood count will be done before and after therapy to detect the effect of the therapy on serum hemoglobin(g/d)
Comparison of efficacy of lactoferrin versus ferrous sulfate tharapy in treatment of patients with iron deficiency anemia.

Time frame: 30 days

Total serum iron(ug/d) will be done before and after therapy to detect effect of the therapy on total serum iron level (ug/d)

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start: 2018
Primary completion: 2018
Study completion: 2018
First posted: Feb 13, 2020
Registry last updated: Feb 13, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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