Laboratory Smoking of Marijuana "Blunts"

Inclusion criteria

• Currently living in Baltimore City or Baltimore County, MD;
• Able to read, understand, and sign informed consent;
• 18-55 years old;
• Currently smokes marijuana blunts;
• Designation of Medically Healthy for Research by the Study Physician; and
• Willing to abstain from illicit drug use other than marijuana for the duration of the study.

Exclusion criteria

• BAC > 0.020% as measured by alcohol breathalyzer;
• Meets DSM-5 criteria for severe current or lifetime Cannabis Use Disorder;
• Meets DSM-5 criteria for any current Axis I disorder, other than current mild or moderate Cannabis Use Disorder;
• Self-reported current desire to stop marijuana use;
• Self-reported current asthma, chronic obstructive pulmonary disease, hypertension, cardiovascular disease or any other medical illness that precludes participation;
• Has difficulties with blood draws or poor venous access;
• History of blood donation in the past 30 days or receiving blood products within the past 2 months prior to any experimental visit;
• Among females, current pregnancy or lactation or attempting to get pregnant, or at risk of becoming pregnant;
• Acute illness which will require participant to be rescheduled