Labor Analgesia With Ropivacaine and Clonidine

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

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Key information

Conditions

Labor Pain Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

Primary location

College of Medicine of Botucatu

Botucatu, São Paulo, 18618970, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Singleton healthy
Full-term pregnancy
American Society of Anesthesiologists physical status I or II

Exclusion criteria

Patients who had received opioids
History of hypersensitivity to local anesthetic or to clonidine
Fetus showed signs of possible intrauterine suffering
Fetus showed signs of possible neurological deficit

Treatment and study plan

Ropivacaine

Drug

15 ml of ropivacaine 0.125% peridural once

ropivacaine and clonidine

Drug

15 ml of ropivacaine 0.0625% plus 75 mcg clonidine

Sponsors and collaborators

Lead sponsor

UPECLIN HC FM Botucatu Unesp

Other

Collaborators

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Faculdade de Medicina de Botucatu, UNESP, Botucatu, Brasil

Registry information

Official study title

Labor Analgesia With Ropivacaine Added to Clonidine. A Randomized Clinical Trial

Acronym: LA

Important dates

Study start: 2000
Primary completion: 2000
Study completion: 2001
First posted: Feb 29, 2008
Registry last updated: Jul 8, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed