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Completed

NCT Number: NCT00647725

Labor Analgesia in the Latent Phrase

Painless labor is an essential part in woman's health care. Labor analgesia in the active phrase is in popular use currently. However, parturients are still haunted by the labor delivery pain in the latent phrase up to 7-8 hours, especially for the nulliparas. Therefore, we hypothesized that labor analgesia in the latent phrase of the first delivery stage would provide superior health care for laboring women. In addition, such analgesia technique would not prolong the time of uterine dilation and labor delivering.

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Key information

Conditions

Labor Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Nanjing Maternal and Child Health Care Hospital

Nanjing, Jiangsu, 210004, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Nulliparas
  • Required labor analgesia
  • Chinese.

Exclusion criteria

  • Allergic to opioids and/or local anesthetics
  • Failed to performing epidural catheterization
  • Organic dysfunction
  • Contraindications for epidural analgesia.

Treatment and study plan

Active phrase epidural analgesia

Procedure

Continuous epidural analgesia with sufentanil plus ropivacaine

Latent phrase epidural analgesia

Procedure

Continuous epidural analgesia with sufentanil plus ropivacaine

Primary outcomes

  1. Rate of Cesarean delivery

    Time frame: The time of the end of the labor

Secondary outcomes

  1. Time of latent phrase

    Time frame: From the beginning of regular contraction of uterus to the diameter of cervix to 4cm

  2. Time of labor

    Time frame: From the beginning of regular contraction of uterus to the end of the labor

  3. Overall feeling of satisfaction of analgesia

    Time frame: From the beginning of regular contraction of uterus to the end of the labor

  4. Side effects

    Time frame: From the beginning of regular contraction of uterus to the end of the labor

  5. VAS pain intensity

    Time frame: From the intinition of analgesia to the cervical dilation >4cm

  6. Instrumental delivery

    Time frame: The end of the time of the labor

  7. Oxytocin infusion rate

    Time frame: During the whole period of laboring

  8. Neonatal Apgar scores

    Time frame: 1st min, 5th min, 10th min and 20th min

  9. Umbilical gas measurement

    Time frame: After delivering of the fetus

  10. Maternal oral temperature

    Time frame: From the initiation of analgesia to the end of the labor

  11. Maternal corticosteroids

    Time frame: 1h before analgesia; 0h of the analgesia; 5min,10min,30min,45min,1h,2h,3h and hourly till the end of the labor

Sponsors and collaborators

Lead sponsor

Nanjing Medical University

Other

Registry information

Official study title

Labor Analgesia in the Latent Phrase of the First-stage of Spontaneous Delivery

Acronym: LALP

Important dates

Study start
2003
Primary completion
2007
Study completion
2007
First posted
Apr 1, 2008
Registry last updated
Oct 1, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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