Skip to main content
OpenTrials
Completed

NCT Number: NCT07436897

Knee Pain and Lumbar Proprioception in Knee Osteoarthritis Patients

Knee osteoarthritis (KOA), is a chronic degenerative joint pathology with a global prevalence of 22.9% in individuals aged 40 and over. It is a leading cause of disability and poor quality of life worldwide due to musculoskeletal pain and functional limitations. Musculoskeletal pain is the primary patient-reported outcome in patients with osteoarthritis (OA) and a major cause of disability and functional limitations this study was carried to investigate the correlation between knee pain and lumbar proprioception

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Osteoarthritis (OA) of the Knee Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Rheumatic Diseases

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Physical therapy College - Cairo university

Cairo, Egypt

About this study

Purpose of the study:

  • To investigate the relationship between knee pain and lumbar proprioception in patient with knee osteoarthritis.
  • To investigate the gender effect on the relationship between knee pain and lumbar proprioception in patient with knee osteoarthritis.
  • To investigate a difference between different grades of knee osteoarthritis on the relationship between lumbar proprioception and knee pain.

fifty-six individuals of both sexes were recruited, their BMI ranged from 24.02 to 29.98. Between the ages of 40 and 60 years Pain was assessd by visual analoge scale and proprioception assessed by The Biodex system

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female participants diagnosed with knee osteoarthritis.
  • The participants diagnosed with grade one, grade two and grade three knee osteoarthritis.
  • Subjects aged form 40-60 years old.
  • All the participants complain of knee pain.
  • Participants able to understand the commands.

Exclusion criteria

  • 1- Experienced serious trauma leading to fractures and dislocations of the spine.

2- They have been diagnosed to have spinal deformities such as scoliosis, lumbar disc herniation and lumbar spondylolisthesis.

3- They have infection/malignant spinal conditions. 4- They have cauda equine syndrome. 5- Anyone with psychological disorders (e.g. dementia or drug abuse). 6- Uncooperative participant 7- Anyone with grade four knee osteoarthritis

Treatment and study plan

porprioception

Other

The Biodex system 3 was used to measure joint position error.

Primary outcomes

  1. proprioception

    Time frame: at the baseline (day 1)

    Joint position error was measured using the Biodex system 3. Before every test, the system was calibrated and stabilized.

    The patient was placed in a seated compressed posture on the Biodex system chair. Two curved pads on the front of the legs allowed for individual adjustment of the knee blocks, and the patient's feet were supported in a way that they did not touch the floor, both thighs were stabilized by two straps, the pelvic brace was then applied and positioned as far down as possible to press firmly but comfortably against the superior aspect of the proximal thighs. The starting position for each participant was with their spines flexed at a 60° angle. As a "target position" for the individuals to maintain during the testing, the predetermined spinal ROM was set at 60° to 90° lumbar flexion. All subjects. After recording the subjects' absolute error (AE) values relative to the 90-degree target position for all three trials, the mean deviation was calculated

Secondary outcomes

  1. Pain intensity

    Time frame: at the baseline (day 1)

    Pain intensity level was measured by applying the VAS. Each participant was made aware that the VAS as being 100 mm horizontal line with one end defined as (no pain = 0 mm), while the other end (Worst pain = 100 mm). Participant was asked to mark a spot on the line between that relates to their level of pain that on a scale of 0-100 mm where 0 mm means absence of pain and 100 mm worst pain. This procedure was repeated three times and average was recorded.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Association Between Knee Pain and Lumbar Proprioception in Patients With Knee Osteoarthritis

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 27, 2026
Registry last updated
Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.