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NCT Number: NCT07239232

"Knee Joint Position Sense and Dynamic Balance in Females With Primary Dysmenorrhea

The purpose of the study is to assess knee joint position sense, pain and dynamic balance in female with primary dysmenorrhea.

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Key information

Conditions

Primary Dysmenorrhea

Age range

18 year–25 year

Sex eligibility

Female

Study type

Observational

Primary location

About this study

Dysmenorrhea is a common condition that typically occurs on its own rather than as a result of pelvic disease. It affects between 50% and 90% of adolescent girls and women of reproductive age and is a major reason for missed days from school or work.

Among the various menstrual disturbances observed, dysmenorrhea was notably prevalent among adolescents and significantly impacted their daily activities. Early diagnosis and awareness of menstrual issues are crucial, as they not only emphasize the need for health education initiatives but also assist in selecting suitable treatments, thereby reducing the adverse effects of these disturbances on adolescents' lives.

However, there is a significant gap in the literature about the effect of Primary dysmenorrhea on knee joint position sense, pain and dynamic balance in young adult female So this study aims to investigate this effect and provide evidence based information in the field of physical therapy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • They should be virgin, healthy female students
  • They have regular menstruation (3-8 days in duration, with 21-35 days in-between).
  • They should have the same activity level mild active female.
  • Their ages will range from 18 to 25 years old.
  • Their body mass index (BMI) will range from 18 to 24.9 Kg/m2.

Exclusion criteria

  • History of knee injury, surgery in the knee or spinal vertebrae.
  • Females having any vestibular problems, otitis media, labyrinthitis or any inner ear problems that affect balance
  • Women with any cognitive deficits
  • History of neuromuscular or spinal disease.
  • History of pelvic pathology or any gynecological disease.

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Overall Stability Index (OSI) . Antero-posterior stability index score (APSI) . Medio lateral stability index score (MLSI) . Over all stability index score (OASI)

    Time frame: at first and fourth menstrual days

    The Overall Stability Index (OSI) is the primary measure of dynamic postural control obtained from the balance assessment system. It reflects the standard deviation of the participant's sway from the platform's center across both the medial-lateral and anterior-posterior directions. Higher OSI values indicate greater instability and poorer balance performance. As an integrated measure of sway variability, the OSI is considered the most comprehensive indicator of overall balance ability and is commonly used to evaluate changes in postural control in response to therapeutic interventions.

  2. Medial-Lateral Stability Index (MLSI)

    Time frame: at first and fourth menstrual days

    The Medial-Lateral Stability Index (MLSI) quantifies the degree of side-to-side sway during balance testing. It represents the standard deviation of medial-lateral movement from the platform's center point, providing a directional measure of postural stability. Elevated MLSI scores reflect increased lateral instability, which may be associated with impaired neuromuscular control or deficits in weight-shifting ability. This variable is useful for identifying balance impairments that predominantly affect frontal plane stability.

  3. Anterior-Posterior Stability Index (APSI)

    Time frame: at first and fourth menstrual days

    The Anterior-Posterior Stability Index (APSI) measures front-to-back sway during dynamic balance assessment. Calculated as the standard deviation of anterior-posterior deviations from the center of the platform, the APSI provides insight into sagittal plane stability. Higher APSI values indicate greater instability and reduced capacity to control forward and backward movements. This index is important for evaluating postural control related to gait, stepping, and activities requiring controlled anterior or posterior shifts in the center of gravity.

  4. knee joint position sense

    Time frame: at first and fourth menstrual days

    using active knee position sense test by universal goniometer.

Secondary outcomes

  1. knee joint pain

    Time frame: at first and fourth menstrual days

    It will be assessed using the Visual analog scale (VAS) for all females in both groups. They will score their level of pain from 1-10, with higher scores indicating more severe pain. It is valid and reliable in pain assessment

Study contacts

Contact information is provided by the study sponsor or research team.

ELHAM s HASSAN, PhD

CONTACT

[email protected]

01206146539

Eman B ABDUL HAMID, B.Sc

CONTACT

[email protected]

01158876852

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Assessment Of Knee Joint Position Sense And Dynamic Balance IN Female With Primary Dysmenorrhea

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 20, 2025
Registry last updated
Dec 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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