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NCT Number: NCT06289218

Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis

The purpose of this study will be to compare the combined effect of using Kinesio taping versus interferential current with an exercise program on knee pain, function, knee range of motion, knee muscle strength, and functional mobility in chronic knee osteoarthritis.

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Key information

Age range

40 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Knee osteoarthritis (KOA) is the most common form of degenerative joint disease affecting 15%-40% of people over 40 years of age. In 2020, the global incidence of KOA was 86.7 million individuals. KOA is responsible for substantial health and economic costs. KOA is the most common cause of pain and disability among older persons. The key symptoms of KOA are pain, functional disability, and decreased patient quality of life through its negative effects on mobility, mood, and sleep. Other symptoms are swelling, stiffness, joint deformity, and muscular atrophy.

The Treatment goals for KOA are to decrease pain and improve physical function. Physical therapy decreased pain and functional disability in patients with KOA. The therapeutic techniques include therapeutic exercises, electrotherapy, and manual therapy. Several meta-analysis and systematic reviews have evidence of various types of exercises including aerobic and resistance exercises which is effective in reducing pain and functional disabilities in a patient with KOA especially quadriceps muscle strengthening with open and closed chain training. Specific recommendations including physical activity, reducing body weight, reducing sedentary time, and managing diabetes disease can improve function and symptoms of KOA. To improve the individual's function, and reduce pain and disability, several interventions had been investigated to promote physical activity.

Kinesio taping (KT) is a conservative therapeutic technique used for the treatment of several musculoskeletal disorders which has increased attention from physicians and physiotherapists in recent years. KT, first introduced in 1979 in Japan, is used for the treatment and prevention of several sports injuries and several clinical conditions. In 2011, KT is recommended by the American College of Rheumatology (ACR) for the treatment of patients with knee OA, and it is commonly used to treat knee OA.

Kinesio taping (KT) is an alternative taping technique which is an elastic woven cotton strip with heat-sensitive acrylic adhesive, a high-stretch elastic adhesive material, it is applied directly to the skin and can be left on the skin for several days due to its strong adherence. The application of KT for four weeks can reduce the pain so the patient can reduce the use pain killers. Kinesio taping (KT) is a low-cost, safe, noninvasive, non-pharmacological method, that has minimal side effects and can be a convenient option for the treatment of musculoskeletal disorders such as knee OA.

Interferential current (IFC) is a simple, non-invasive, non-pharmacological, more comfortable treatment used to relieve pain. IFC known as kilohertz-frequency alternating current, which is a pair of signal generators with one fixed frequency of 4000 Hz and the other varying in frequency between 4000 and 4250 Hz. IFC can reduce skin impedance, reach deeper tissue, and can be utilized as an alternative medication or supplement to drugs in treating pain. IFC is the most effective pain relief treatment for the management of KOA.

Exercises play a major role in treating patients with KOA; it can improve both pain and function. Therefore What about comparing the application of kinesio taping combined with exercises versus the IFC therapy combined with exercises in treating patients with KOA?

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • sixty-three Male and female patients aged between 40 and 65 years old were diagnosed clinically and radiologically as knee osteoarthritis grade mild and moderate chronic knee osteoarthritis.
  • BMI ranges between 20 and 32 kg/m2.
  • Knee OA grades 1 and 2 are based on Kellgren and Lawrence's grades. Narrowing of joint space, definite osteophytes.
  • Unilateral knee osteoarthritis.
  • Knee pain for most days of the prior month, in addition to at least 3 of the following:
  • Crepitus on active joint motion
  • Morning stiffness less than 30 minutes duration
  • Age older than 50 years
  • Bony enlargement of the knee on examination
  • Bony tenderness of the knee on examination
  • No palpable warmth.

Exclusion criteria

  • Patients having the following conditions will be excluded from the study:
  • Comorbidities such as (rheumatoid arthritis, cancer, osteoporosis, and joint infection).
  • Previous surgery for knee OA.
  • BMI more than 33 kg/m2.
  • Suffering from polyarticular disease.
  • Severe mechanical deformity (diaphyseal Varus deformity of 4° and valgus of 16°).
  • Previous arthroscopy within the last year.
  • Systemic autoimmune rheumatoid disease (connective tissue disease and systemic necrotizing vasculitis).

Treatment and study plan

Interferential Current

Device

IFC plus exercise

Other names: IFC

Kinesio Taping

Other

KT plus exercise

Other names: KT

Exercise

Other

exercise only

Primary outcomes

  1. knee flexion range of motion

    Time frame: pre-intervention and after 4 weeks of treatment

    to measure Knee joint active range of motion (flexion) by universal goniometer

  2. knee extension range of motion

    Time frame: pre-intervention and after 4 weeks of treatment

    to measure Knee joint active range of motion (extension) by universal goniometer

  3. quadriceps muscle strength

    Time frame: pre-intervention and after 4 weeks of treatment

    to test the isometric quadriceps muscle strength by hand-held dynamometer

  4. The Western Ontario and McMaster Universities Osteoarthritis Index

    Time frame: pre-intervention and after 4 weeks of treatment

    to measure knee function and knee pain degree

  5. Timed up and go test

    Time frame: pre-intervention and after 4 weeks of treatment

    to measure knee function mobility by the Timed up and go test

Study contacts

Contact information is provided by the study sponsor or research team.

Marihan Zakaria Aziz Makary, Dr

CONTACT

[email protected]

01201227971

Nourhan Elsaid Ahmed Elsaid

CONTACT

[email protected]

966540792567

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Kinesio Taping Versus Interferential Current Therapy in Treating Knee Osteoarthritis: a Comparative Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 1, 2024
Registry last updated
May 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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