Skip to main content
OpenTrials
Completed

NCT Number: NCT04389983

Ketone Levels Achieved After Medium Chain Triglyceride (MCT) Oil

Assessing Ketone levels achieved after varying doses of Medium Chain Triglyceride (MCT) oil

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pharmacokinetics

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Alberta

Edmonton, Alberta, T6G 2P4, Canada

About this study

Assessing Ketone levels achieved after varying doses of Medium Chain Triglyceride (MCT) oil in three study populations: <65 year healthy, 65 and older healthy, and Alzheimer's disease.

Each subject attends for 4 study days, receiving incrementally larger MCT doses at each visit for 0g, to 14g, to 28g to 42g.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult, healthy or with AD

Exclusion criteria

  • unable to attend all study days
  • coconut allergy
  • Diabetes

Treatment and study plan

Medium Chain Triglyceride oil

Dietary Supplement

Bulletproof Braine Octane MCT oil

Primary outcomes

  1. Maximum plasma concentration (Cmax)

    Time frame: 3 months

    Calculation of Cmax to varying doses in each subject and in different study arms.

  2. Time to maximum plasma concentration (tmax)

    Time frame: 3 months

    Calculation of tmax to varying doses in each subject and in different study arms.

  3. Area under the curve (AUC)

    Time frame: 3 months

    Calculation of AUC to varying doses in each subject and in different study arms.

Secondary outcomes

  1. weight

    Time frame: 3months

    measured in kg

  2. height

    Time frame: 3 months

    measured in cm

  3. BMI

    Time frame: 3months

    Calculated BMI (ht/m2)

  4. Body fat

    Time frame: 3 months

    % measured by bioimpedence scale

Sponsors and collaborators

Lead sponsor

University of Alberta

Other

Registry information

Important dates

Study start
2019
Primary completion
2019
Study completion
2020
First posted
May 15, 2020
Registry last updated
May 15, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.