Skip to main content
OpenTrials
Completed

NCT Number: NCT03060070

Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block

Comparing the analgesic effects of ketamine and dexmedetomidine when added to local anesthetic in TAP block for postoperative analgesia after lower abdominal cancer surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Analgesia Lower Abdominal Cancer

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

South Egypt Cancer Institute

Asyut, Assiut University, 171516, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients ASA I and II to whom abdominal surgery for cancer will be conducted will be included in the study

Exclusion criteria

  • Coagulopathies
  • ASA III or IV, patient refusal, sensitivity to the used drugs

Treatment and study plan

ketamine

Drug

Ketamine at a dose of 0.5mg/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block

Dexmedetomidine

Drug

dexmedetomidine at a dose of 1ug/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block

Control group

Drug

20ml of 0.25% bupivacaine will be injected in each side of the TAP block

Primary outcomes

  1. postoperative rescue morphine consumption

    Time frame: 24 hours postoperative

    postoperative rescue morphine consumption

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Collaborators

  • South Egypt Cancer Institute

Registry information

Official study title

Comparison of the Analgesic Effect of Ketamine Versus Dexmedetomidine Added to Local Anesthetic in TAP Block for Lower Abdominal Cancer Surgery

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Feb 23, 2017
Registry last updated
Jul 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.