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NCT Number: NCT07682610

Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Health Services Research Intervention

This clinical trial studies statewide optimization of lung cancer screening (LCS) in Kentucky using the Quality Implementation of Lung Screening (QUILS™) System. Data from the Kentucky Cancer Registry shows that LCS implementation has contributed to a rapid decline in late-stage lung cancer diagnosis at twice the national average. Further, the declines are more than three times the national average decline in Kentucky's Central Appalachian region. Kentucky-based multilevel initiatives are needed to expand and accelerate this leading role and extend the LCS opportunity to more Kentuckians who are at increased risk of lung cancer. This trial may be able to accelerate optimal high-quality implementation of LCS utilizing the QUILS™ System and reduce the burden of lung cancer by assisting lung cancer screening programs located throughout Kentucky in implementing best practices in lung cancer screening by integrating the QUILS™ System domains and elements into their screening programs.

Recruiting

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Key information

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

King's Daughter's Medical Center, Ashland, Kentucky, United States

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Member of a participating Lung Cancer Screening Program (LCSP) team or administrator
  • Willing to participate in the QUILS Index Assessment Survey process
  • Willing to participate in the QUILS Audit Feedback presentations
  • Willing to participate in formative evaluation interviews

Exclusion criteria

  • Unwilling to participate in the QUILS Index Assessment Survey process
  • Unwilling to participate in the QUILS Audit Feedback presentations
  • Unwilling to participate in formative evaluation interviews

Treatment and study plan

Quality Implementation of Lung Cancer Screening (QUILS) System

Behavioral

The QUILS System is a health services research intervention designed to improve the quality of lung cancer screening programs. The intervention includes QUILS Index Assessment, QUILS Audit and Feedback Report and Presentation, QUILS Resource Portal, site-specific action plans, and formative evaluation activities.

Primary outcomes

  1. Change in Quality Improvement Lung Cancer Screening (QUILS) Index Assessment Score

    Time frame: Baseline and Month 9

    The QUILS Index Assessment is a program-level measure of lung cancer screening implementation quality. Scores range from 0 to 95, with a higher score indicating higher quality implementation of lung cancer screening practices. The outcome measure is the change in total QUILS Index score from Baseline to 12 months.

Study contacts

Contact information is provided by the study sponsor or research team.

Joseph Alexander, MD

CONTACT

[email protected]

8593230892

Sponsors and collaborators

Lead sponsor

Timothy Mullett

Other

Registry information

Official study title

Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System (Kentucky QUILS™ Implementation): HSR Intervention

Important dates

Study start
2025
Primary completion
2027
Study completion
2028
First posted
Jul 6, 2026
Registry last updated
Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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