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NCT Number: NCT05800535

JUMP Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients

Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease. Thus, the reconquest of a life after cancer becomes possible but raises many challenges for the patient, his entourage, the medical profession and our society. One of the major challenges is the detection and management of treatment side effects for all patients. In addition to the standard organic assessment (glycaemia, creatinine, liver test, blood count), we are mainly interested in muscle deconditioning and cognitive impairment, which are particularly disturbed in these populations. After the evaluation day, patients are referred to the most appropriate structures (Adapted physical activity, sports for health, and rehabilitation at Henry Gabriel Hospital).

JUMP research is part of axis 2 of the 2021-2030 cancer plan: "Limiting sequelae and improving quality of life", through sheets 1 (research) / 6 (access and quality) / 7 (prevention). This leads to the concrete implementation on the territory of adapted care channels in the city: medical structure, physiotherapy, Adapted Physical Activity (APA) structures, associative structures; which makes it possible to develop and strengthen the city-hospital link. Finally, it allows the patient to take ownership and get involved in the project, allowing in the future to make them truly active in they care and to advise and motivate their peers.

This study is non-interventional, it uses research on data that is already collected as part of conventional care, during the JUMP evaluation day.

This study allows the investigators to constitute a cohort of patients to study different parameters related to the disease or to the treatments received.

Our main objective in this study is to describe the muscular and neurocognitive impairment of post-cancer patients evaluated as part of the JUMP program.

Recruiting

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Key information

Age range

18 year–74 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Rhumatologie, Hospices Civils de Lyon, Groupement Hospitalier Lyon Sud

Pierre-Bénite, 69310, France

Location status: Recruiting

Location contact

Cyrille CONFAVREUX, PR

CONTACT

[email protected]

4 78 86 12 31 ext. +33

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age : 18 to 74 years
  • localization of the primitive: breast, lung, melanoma, testicle, bladder, kidney, ovary, colon and pancreas, hemopathy
  • patient who benefited from the post-cancer assessment day-

Exclusion criteria

  • Under 18years
  • Over 74 years
  • Patient who did not received any chemical treatment
  • Patient who do not wish to participate

Treatment and study plan

Study of the adverse effects of long-term oncological treatments

Drug

Cognitive and muscular evaluation of patients who have received oncological treatments, away from the latest treatments to assess their impacts

Study of the long-term side effects of oncological treatments on the anxiety-depressive and cognitive state of patients

Behavioral

Cognitive and anxiety-depressive evaluation of patients who have received oncological treatments, away from the latest treatments to assess their impacts

Primary outcomes

  1. Prevalence of patients with physical and neurocognitive impairment

    Time frame: at least 1 year later after chemical treatments

    Number of patients whose medical assessments show altered physical, cognitive or anxiety/dpression activity compared to the measurement in the general population

Study contacts

Contact information is provided by the study sponsor or research team.

Cyrille CONFAVREUX, MD

CONTACT

[email protected]

+334 78 86 12 31

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients

Acronym: JUMP

Important dates

Study start
2025
Primary completion
2029
Study completion
2029
First posted
Apr 5, 2023
Registry last updated
Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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