Completed

NCT Number: NCT02002494

Jugular Venous Flow Healthy Volunteers

Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow in the between right and left internal jugular veins in park bench position, particularly there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine position.

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Key information

Conditions

Jugular Venous Blood Flow

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Health Network, Toronto Western Hospital

Toronto, Ontario, M5T 2S8, Canada

About this study

The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.

Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult healthy volunteers who are above the age of 18
American Society of Anesthesiologists classification (ASA) 1
Body mass index (BMI) less than and equal to 35

Exclusion criteria

ASA 2 and above
BMI above 35
Lack of informed consent
Language barrier
Medical students and anaesthesia residents going through the department as part of their rotation

Treatment and study plan

Different positions

Other

Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench

Primary outcomes

Internal Jugular Venous (IJV) Cross Sectional Area

Time frame: 1 day

Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions.
Right and Left IJV Cross Sectional Area

Time frame: 1 day

Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench
Internal Jugular Venous (IJV) Doppler Velocity

Time frame: 1 day

27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions
Bilateral Internal Jugular Vein (IJV) Flow

Time frame: 1 day

Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) .
Bilateral Internal Jugular Vein (IJV) Doppler Velocity

Time frame: 1 day

Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position.
R IJV and L IJV Flow

Time frame: 1 day

Bilateral internal jugular vein (IJV) flow between supine and right park bench position.

Sponsors and collaborators

Lead sponsor

University Health Network, Toronto

Other

Registry information

Official study title

Effect of Different Surgical Positions on the Cerebral Venous Drainage: an Ultrasound Study on Healthy Volunteers

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2014
First posted: Dec 5, 2013
Registry last updated: Jun 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.