JIT: Effect of Pain on DT in TMD

Inclusion criteria

• Participants in this study must be 21 years to 65 years of age and provide a driver's license or other state-issued ID.
• Participants must also be sufficiently fluent in English to provide informed consent and understand questionnaires and instructions for laboratory procedures.
• Participants must report drinking of, on average, at least 1 drink 3 days/week over the past 6 months.
• Meet Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for myalgia (masticatory muscle pain), arthralgia (TMJ pain), or a combination (Schiffman et al., 2014) (TMD group only).
• Own a smartphone with internet access.
• Use of prescription medications will be allowed, provided they do not contraindicate alcohol use.

Exclusion criteria

• Use of opioid analgesics within the past month;
• Current major depression;
• History of any psychotic disorder;
• Under-controlled hypertension or diabetes (as reflected by self-report); neurological disease (e.g., multiple sclerosis, epilepsy, amyotrophic lateral sclerosis, Parkinson's disease);
• Serious medical illness (e.g., hepatitis, HIV/AIDS);
• Impaired cognitive function;
• History of substance use disorder (including nicotine/tobacco);
• Alcohol naïve
• Alcohol use disorder, or currently attempting to quit or cut down on using alcohol
• Positive pregnancy test
• Breastfeeding or intending to become pregnant
• Loss of sensation in the lower leg
• Inability to complete study tasks due to weakness, immobilization, or loss of limbs
• Chronic pain (Control group only)
• A urine-based drug screen for tetrahydrocannabinol, cocaine, benzodiazepines, morphine, and methamphetamine (Innovacon, Inc., San Diego, CA) will be performed. Participants testing positive for any substance will be discontinued.
• Medications that contraindicate alcohol use