IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular Contractions (PVC). The registry will be used for clinical monitoring, research, and quality improvement purposes.

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Key information

Conditions

Ventricular Arrhythmia Arrhythmias, Cardiac Cardiac Complexes, Premature Cardiac Conduction System Disease Cardiomyopathies Cardiomyopathy Cardiovascular Diseases Death Death, Sudden Death, Sudden, Cardiac Heart Arrest Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Premature Ventricular Contraction (PVC) Tachycardia Tachycardia, Ventricular Ventricular Premature Complexes Ventricular Tachycardia

Sex eligibility

All sexes

Study type

Observational

Primary location

The Montreal Heart Institute, Montreal, Canada

About this study

Sudden cardiac death (SCD), predominantly due to ventricular tachyarrhythmias, is a leading cause of mortality in the United States and around the world. Catheter ablation of ventricular arrhythmias has proven efficacious in reducing the burden of arrhythmias and reducing implantable cardiac defibrillator (ICD) shocks.

The aim of this study is to create a prospective international database registry that will allow for better assessment of the outcomes of catheter ablation of ventricular arrhythmias. The registry, with approximately 30 participating centers, will help to identify the overall success rates and associated benefits of the procedure and provide more comprehensive data on understudied populations and treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients undergoing catheter ablation for ventricular tachycardia (VT) or premature ventricular contractions (PVCs).

Treatment and study plan

Primary outcomes

Ventricular tachycardia (VT) recurrence

Time frame: From date of procedure assessed by shock, Anti-Tachycardia Pacing, or repeat procedure, up to 10 years.

Freedom from ventricular tachycardia episodes requiring ICD Intervention (shock or Anti-Tachycardia Pacing) or repeat procedure.

Secondary outcomes

Rate of complications

Time frame: From date of procedure assessed up to 12 months.

Cardiovascular-related and procedure-related major complications and/or adverse events.
Time to transplant or death

Time frame: From date of procedure assessed by date of transplant and/or death, up to 10 years.

Sponsors and collaborators

Lead sponsor

University of California, Los Angeles

Other

Registry information

Official study title

An International VT Ablation Center Collaborative Group (IVTCC): A Multicenter Ventricular Tachycardia Catheter Ablation Registry

Acronym: IVTCC

Important dates

Study start: 2018
Primary completion: 2026
Study completion: 2027
First posted: Aug 20, 2020
Registry last updated: Dec 15, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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