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NCT Number: NCT07549165

IVC Collapsibility Index in Lumbar Stabilization Surgery

This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia. The IVC diameter and collapsibility index will be measured using ultrasonography at predefined perioperative time points. Hemodynamic parameters such as blood pressure and heart rate will also be recorded. The study seeks to determine whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and hemodynamic changes during lumbar spine surgery.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Trabzon University Faculty of Medicine Kanunı Training and Research Hospital ,Trabzon, Trabzon, Turkey (Türkiye)

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About this study

his prospective study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia in the prone position. The inferior vena cava diameter will be measured using ultrasonography at different perioperative time points, including the preoperative period, after induction of anesthesia, and before extubation.

The IVC diameter and collapsibility index will be recorded and analyzed to assess changes in intravascular volume status during the perioperative period. In addition to ultrasonographic measurements, hemodynamic parameters such as blood pressure and heart rate will be monitored and recorded.

The study aims to investigate whether the IVC collapsibility index can be used as a non-invasive indicator of intravascular volume status and perioperative hemodynamic changes in patients undergoing lumbar spine surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years
  • Patients classified as ASA physical status I-II-III
  • Patients scheduled for elective lumbar spine stabilization surgery under general anesthesia
  • Ability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
  • Provision of written informed consent

Exclusion criteria

  • Age younger than 18 years
  • Emergency surgery
  • American Society of Anesthesiologists (ASA) physical status IV
  • Patients undergoing revision lumbar stabilization surgery
  • Baseline systolic blood pressure >180 mmHg or <90 mmHg
  • Heart failure with ejection fraction (EF) <40%
  • Pulmonary artery pressure (PAP) >40 mmHg
  • Presence of intra-abdominal mass, ascites, or increased intra-abdominal pressure
  • Body mass index (BMI) >30 kg/m²
  • Pregnancy
  • Patients with neurological or psychiatric disorders
  • Inability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging
  • Refusal to provide written informed consent

Treatment and study plan

Primary outcomes

  1. Inferior Vena Cava Collapsibility Index

    Time frame: Perioperative period (preoperative assessment, after anesthesia induction, and before extubation)

    The inferior vena cava (IVC) collapsibility index will be measured using ultrasonography at predefined perioperative time points (preoperative period, after induction of general anesthesia, and before extubation) in patients undergoing elective lumbar spine surgery in the prone position.

Secondary outcomes

  1. Intraoperative Hypotension Incidence

    Time frame: During the intraoperative period

    The occurrence of intraoperative hypotension during lumbar spine surgery under general anesthesia will be recorded. Hypotension will be defined as mean arterial pressure below 65 mmHg.

Study contacts

Contact information is provided by the study sponsor or research team.

Şeyma Yüksel Ayar, MD

CONTACT

[email protected]

+905395655853

Sponsors and collaborators

Lead sponsor

Trabzon Kanuni Education and Research Hospital

Other

Registry information

Official study title

Hemodynamic Assessment Using the Inferior Vena Cava Collapsibility Index in Patients Undergoing Lumbar Stabilization Surgery

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 23, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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