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Completed

NCT Number: NCT00000212

IV Cocaine Abuse: A Laboratory Model - 1

The purpose of this study is to evaluate the effects of desipramine DMI maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Columbia University

New York, 10023, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Please contact site for information.

Treatment and study plan

Desipramine

Drug

Primary outcomes

  1. Amount cocaine self-administered

  2. Direct cocaine effects (cardiovascular, subjective

  3. Interaction of cocaine and DMI on cardio measures

  4. Interaction of cocaine/DMI on coc's subjective

  5. Effects of DMI on cocaine craving

  6. Drug use during outpatient DMI maintenance

Sponsors and collaborators

Lead sponsor

New York State Psychiatric Institute

Other

Collaborators

  • Columbia University
  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

IV Cocaine Abuse: A Laboratory Model

Important dates

Study start
1987
Primary completion
1988
Study completion
1988
First posted
Sep 21, 1999
Registry last updated
Aug 31, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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