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OpenTrials
Completed

NCT Number: NCT01025557

Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response

The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.

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Key information

Age range

20 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

University of Toronto

Toronto, Ontario, M5S 3E2, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy
  • Non-smoking
  • Aged 20-30 years
  • Body mass index between 20 and 24.9 kg/m2

Exclusion criteria

  • Diabetes
  • Medication
  • Lactose-intolerance or allergies to milk
  • Breakfast skippers and those on an energy restricted diet

Treatment and study plan

Dietary Intervention

Other

Dietary treatments with beverages

Primary outcomes

  1. Food intake

    Time frame: 30 minute

Secondary outcomes

  1. Blood glucose

    Time frame: 0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes

Sponsors and collaborators

Lead sponsor

University of Toronto

Other

Collaborators

  • Dairy Farmers of Ontario
  • Mondelēz International, Inc.
  • Natural Sciences and Engineering Research Council, Canada

Registry information

Official study title

The Effects of Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response in Healthy Young Men and Women

Important dates

Study start
2009
Primary completion
2011
Study completion
2012
First posted
Dec 3, 2009
Registry last updated
Jun 14, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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